OMIA group 168
Cataract, generic
The chain
From the animal disease to the drugs. The page shows what each step found and where the chain stopped. It does not say whether the animal is a model of a human disease.
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Animal disease
Reached
OMIA records it in 28 species entries marked as a defect.
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Human disease
Stopped here
Neither OMIA's own Mondo link nor its OMIM numbers lead to a Mondo disease.
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Human gene
Not reached
The chain stopped before this step.
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Target evidence
Not reached
The chain stopped before this step.
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Drugs
Not reached
The chain stopped before this step.
The chain stopped at Human disease: Neither OMIA's own Mondo link nor its OMIM numbers lead to a Mondo disease.
Natural-model score
How complete and how well supported the chain to each human disease is, out of 100, by stated rules. It does not say that the animal is a validated model of the human disease. How the score works.
This group reaches no human disease, so it has no score.
Species
The chain follows only the species entries that OMIA marks as a defect.
| Species | Scientific name | OMIA entry | A defect |
|---|---|---|---|
| Adelie penguin | Pygoscelis adeliae | OMIA:000168-9238 | Yes |
| African penguin | Spheniscus demersus | OMIA:000168-92683 | Yes |
| American black bear | Ursus americanus | OMIA:000168-9643 | Yes |
| bald eagle | Haliaeetus leucocephalus | OMIA:000168-52644 | Yes |
| chicken | Gallus gallus | OMIA:000168-9031 | Yes |
| chinstrap penguin | Pygoscelis antarcticus | OMIA:000168-79643 | Unknown, not counted |
| crab-eating macaque | Macaca fascicularis | OMIA:000168-9541 | Yes |
| degu | Octodon degus | OMIA:000168-10160 | Yes |
| dog | Canis lupus familiaris | OMIA:000168-9615 | Yes |
| domestic cat | Felis catus | OMIA:000168-9685 | Yes |
| domestic cattle | Bos taurus | OMIA:000168-9913 | Yes |
| domestic ferret | Mustela putorius furo | OMIA:000168-9669 | Yes |
| domestic guinea pig | Cavia porcellus | OMIA:000168-10141 | Yes |
| donkey | Equus asinus | OMIA:000168-9793 | Yes |
| Gentoo penguin | Pygoscelis papua | OMIA:000168-30457 | Yes |
| giant panda | Ailuropoda melanoleuca | OMIA:000168-9646 | Yes |
| Gray red-backed vole | Craseomys rufocanus | OMIA:000168-527686 | Yes |
| green monkey | Chlorocebus sabaeus | OMIA:000168-60711 | Yes |
| grivet monkey | Chlorocebus aethiops | OMIA:000168-9534 | Yes |
| horse | Equus caballus | OMIA:000168-9796 | Yes |
| Humboldt's penguin | Spheniscus humboldti | OMIA:000168-9240 | Yes |
| king penguin | Aptenodytes patagonicus | OMIA:000168-9234 | Yes |
| lion | Panthera leo | OMIA:000168-9689 | Yes |
| Magellanic penguin | Spheniscus magellanicus | OMIA:000168-37081 | Yes |
| rabbit | Oryctolagus cuniculus | OMIA:000168-9986 | Yes |
| Rockhopper penguin | Eudyptes chrysocome | OMIA:000168-79626 | Yes |
| sheep | Ovis aries | OMIA:000168-9940 | Yes |
| thirteen-lined ground squirrel | Ictidomys tridecemlineatus | OMIA:000168-43179 | Yes |
| West Indian manatee | Trichechus manatus | OMIA:000168-9778 | Yes |
Genes
Each gene OMIA records for a species entry, and the human gene it reaches through Ensembl's orthologs.
| Species | Animal gene | Human gene | Ortholog |
|---|---|---|---|
| Adelie penguin | No gene | OMIA records no gene for this species entry. | |
| African penguin | No gene | OMIA records no gene for this species entry. | |
| American black bear | No gene | OMIA records no gene for this species entry. | |
| bald eagle | No gene | OMIA records no gene for this species entry. | |
| chicken | No gene | OMIA records no gene for this species entry. | |
| crab-eating macaque | No gene | OMIA records no gene for this species entry. | |
| degu | No gene | OMIA records no gene for this species entry. | |
| dog | No gene | OMIA records no gene for this species entry. | |
| domestic cat | No gene | OMIA records no gene for this species entry. | |
| domestic cattle | No gene | OMIA records no gene for this species entry. | |
| domestic ferret | No gene | OMIA records no gene for this species entry. | |
| domestic guinea pig | Cryz crystallin, zeta (quinone reductase) NCBI Gene 100135507 | CRYZ Ensembl | one to one |
| donkey | No gene | OMIA records no gene for this species entry. | |
| Gentoo penguin | No gene | OMIA records no gene for this species entry. | |
| giant panda | No gene | OMIA records no gene for this species entry. | |
| Gray red-backed vole | No gene | OMIA records no gene for this species entry. | |
| green monkey | No gene | OMIA records no gene for this species entry. | |
| grivet monkey | No gene | OMIA records no gene for this species entry. | |
| horse | No gene | OMIA records no gene for this species entry. | |
| Humboldt's penguin | No gene | OMIA records no gene for this species entry. | |
| king penguin | No gene | OMIA records no gene for this species entry. | |
| lion | No gene | OMIA records no gene for this species entry. | |
| Magellanic penguin | No gene | OMIA records no gene for this species entry. | |
| rabbit | No gene | OMIA records no gene for this species entry. | |
| Rockhopper penguin | No gene | OMIA records no gene for this species entry. | |
| sheep | No gene | OMIA records no gene for this species entry. | |
| thirteen-lined ground squirrel | No gene | OMIA records no gene for this species entry. | |
| West Indian manatee | No gene | OMIA records no gene for this species entry. | |
| chinstrap penguin Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
Human diseases
Two routes lead from an OMIA group to a Mondo human disease: OMIA's own Mondo link, and the group's OMIM numbers through Mondo's cross-references.
- OMIA's own Mondo link: OMIA links the group to no Mondo disease.
- OMIA's OMIM numbers: OMIA gives the group no OMIM number marked as a trait.
The chain did not reach a human disease.
Target evidence
Each Open Targets association between one of the group's human genes and one of its human diseases, with its overall score and the score for each kind of evidence.
The chain did not reach target evidence.
Drugs
The chain did not reach the drugs.