OMIA group 1744
Mastitis, predisposition to
The chain
From the animal disease to the drugs. The page shows what each step found and where the chain stopped. It does not say whether the animal is a model of a human disease.
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Animal disease
Reached
OMIA records it in 4 species entries marked as a defect.
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Human disease
Stopped here
Neither OMIA's own Mondo link nor its OMIM numbers lead to a Mondo disease.
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Human gene
Not reached
The chain stopped before this step.
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Target evidence
Not reached
The chain stopped before this step.
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Drugs
Not reached
The chain stopped before this step.
The chain stopped at Human disease: Neither OMIA's own Mondo link nor its OMIM numbers lead to a Mondo disease.
Natural-model score
How complete and how well supported the chain to each human disease is, out of 100, by stated rules. It does not say that the animal is a validated model of the human disease. How the score works.
This group reaches no human disease, so it has no score.
Species
The chain follows only the species entries that OMIA marks as a defect.
| Species | Scientific name | OMIA entry | A defect |
|---|---|---|---|
| domestic cattle Naturally occurring, and also genetically engineered. | Bos taurus | OMIA:001744-9913 | No, not counted |
| goat Naturally occurring, and also genetically engineered. | Capra hircus | OMIA:001744-9925 | No, not counted |
| rabbit | Oryctolagus cuniculus | OMIA:001744-9986 | Yes |
| sheep Naturally occurring, and also genetically engineered. | Ovis aries | OMIA:001744-9940 | Yes |
| water buffalo | Bubalus bubalis | OMIA:001744-89462 | Yes |
| zebu cattle | Bos indicus | OMIA:001744-9915 | Yes |
Genes
Each gene OMIA records for a species entry, and the human gene it reaches through Ensembl's orthologs.
| Species | Animal gene | Human gene | Ortholog |
|---|---|---|---|
| rabbit | No gene | OMIA records no gene for this species entry. | |
| sheep | SOCS2 suppressor of cytokine signaling 2 NCBI Gene 101115017 | SOCS2 Ensembl | one to one |
| water buffalo | No gene | OMIA records no gene for this species entry. | |
| zebu cattle | No gene | OMIA records no gene for this species entry. | |
| domestic cattle Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| goat Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
Human diseases
Two routes lead from an OMIA group to a Mondo human disease: OMIA's own Mondo link, and the group's OMIM numbers through Mondo's cross-references.
- OMIA's own Mondo link: OMIA links the group to no Mondo disease.
- OMIA's OMIM numbers: OMIA gives the group no OMIM number marked as a trait.
The chain did not reach a human disease.
Target evidence
Each Open Targets association between one of the group's human genes and one of its human diseases, with its overall score and the score for each kind of evidence.
The chain did not reach target evidence.
Drugs
The chain did not reach the drugs.