OMIA group 2665
Genetically engineered humanised animal
The chain
From the animal disease to the drugs. The page shows what each step found and where the chain stopped. It does not say whether the animal is a model of a human disease.
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Animal disease
Reached
OMIA records it in 1 species entry marked as a defect.
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Human disease
Stopped here
Neither OMIA's own Mondo link nor its OMIM numbers lead to a Mondo disease.
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Human gene
Not reached
The chain stopped before this step.
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Target evidence
Not reached
The chain stopped before this step.
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Drugs
Not reached
The chain stopped before this step.
The chain stopped at Human disease: Neither OMIA's own Mondo link nor its OMIM numbers lead to a Mondo disease.
Natural-model score
How complete and how well supported the chain to each human disease is, out of 100, by stated rules. It does not say that the animal is a validated model of the human disease. How the score works.
This group reaches no human disease, so it has no score.
Species
The chain follows only the species entries that OMIA marks as a defect.
| Species | Scientific name | OMIA entry | A defect |
|---|---|---|---|
| chicken Genetically engineered, not naturally occurring. Not counted in the score. | Gallus gallus | OMIA:002665-9031 | Unknown, not counted |
| crab-eating macaque | Macaca fascicularis | OMIA:002665-9541 | Yes |
| domestic cattle Genetically engineered, not naturally occurring. Not counted in the score. | Bos taurus | OMIA:002665-9913 | No, not counted |
| goat Genetically engineered, not naturally occurring. Not counted in the score. | Capra hircus | OMIA:002665-9925 | No, not counted |
| golden hamster Genetically engineered, not naturally occurring. Not counted in the score. | Mesocricetus auratus | OMIA:002665-10036 | Unknown, not counted |
| pig Genetically engineered, not naturally occurring. Not counted in the score. | Sus scrofa | OMIA:002665-9823 | No, not counted |
| rabbit Genetically engineered, not naturally occurring. Not counted in the score. | Oryctolagus cuniculus | OMIA:002665-9986 | No, not counted |
| Rhesus monkey Genetically engineered, not naturally occurring. Not counted in the score. | Macaca mulatta | OMIA:002665-9544 | Unknown, not counted |
| sheep Genetically engineered, not naturally occurring. Not counted in the score. | Ovis aries | OMIA:002665-9940 | Unknown, not counted |
Genes
Each gene OMIA records for a species entry, and the human gene it reaches through Ensembl's orthologs.
| Species | Animal gene | Human gene | Ortholog |
|---|---|---|---|
| crab-eating macaque | No gene | OMIA records no gene for this species entry. | |
| chicken Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| domestic cattle Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| goat Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| golden hamster Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| pig Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| rabbit Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| Rhesus monkey Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| sheep Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
Human diseases
Two routes lead from an OMIA group to a Mondo human disease: OMIA's own Mondo link, and the group's OMIM numbers through Mondo's cross-references.
- OMIA's own Mondo link: OMIA links the group to no Mondo disease.
- OMIA's OMIM numbers: OMIA gives the group no OMIM number marked as a trait.
The chain did not reach a human disease.
Target evidence
Each Open Targets association between one of the group's human genes and one of its human diseases, with its overall score and the score for each kind of evidence.
The chain did not reach target evidence.
Drugs
The chain did not reach the drugs.