OMIA group 2686
Colour vision, deficiency
The chain reaches the human disease color vision disorder, which Mondo defines as: “The absence of or defect in the perception of colors.” It reaches 1 more human disease, listed below.
The chain
From the animal disease to the drugs. The page shows what each step found and where the chain stopped. It does not say whether the animal is a model of a human disease.
-
Animal disease
Reached
OMIA records it in 4 species entries marked as a defect.
-
Human disease
Reached
2 Mondo diseases.
-
Human gene
Stopped here
No gene of a species entry marked as a defect reaches a human gene through Ensembl's orthologs.
-
Target evidence
Not reached
The chain stopped before this step.
-
Drugs
Not reached
The chain stopped before this step.
The chain stopped at Human gene: No gene of a species entry marked as a defect reaches a human gene through Ensembl's orthologs.
Natural-model score
How complete and how well supported the chain to each human disease is, out of 100, by stated rules. It does not say that the animal is a validated model of the human disease. How the score works.
15.0 out of 100
| Part | Computed from | Points |
|---|---|---|
| Target evidence | No Open Targets association with this disease | 0.0 of 35 |
| Drugs | No drug has been tested for this disease, and none acts on its genes | 0.0 of 25 |
| Ortholog | No gene of a naturally occurring entry reaches a human gene | 0.0 of 20 |
| Both routes | One route found this disease | 5.0 of 10 |
| Species | 4 naturally occurring species entries marked as a defect | 10.0 of 10 |
15.0 out of 100
| Part | Computed from | Points |
|---|---|---|
| Target evidence | No Open Targets association with this disease | 0.0 of 35 |
| Drugs | No drug has been tested for this disease, and none acts on its genes | 0.0 of 25 |
| Ortholog | No gene of a naturally occurring entry reaches a human gene | 0.0 of 20 |
| Both routes | One route found this disease | 5.0 of 10 |
| Species | 4 naturally occurring species entries marked as a defect | 10.0 of 10 |
Species
The chain follows only the species entries that OMIA marks as a defect.
| Species | Scientific name | OMIA entry | A defect |
|---|---|---|---|
| Australian swellshark | Cephaloscyllium laticeps | OMIA:002686-335038 | No, not counted |
| crab-eating macaque | Macaca fascicularis | OMIA:002686-9541 | Yes |
| dusky shark | Carcharhinus obscurus | OMIA:002686-7807 | No, not counted |
| great white shark | Carcharodon carcharias | OMIA:002686-13397 | No, not counted |
| gummy shark | Mustelus antarcticus | OMIA:002686-7813 | No, not counted |
| Japanese medaka | Oryzias latipes | OMIA:002686-8090 | Yes |
| lemon shark | Negaprion brevirostris | OMIA:002686-7821 | No, not counted |
| Port Jackson shark | Heterodontus portusjacksoni | OMIA:002686-7793 | No, not counted |
| shortfin mako shark | Isurus oxyrinchus | OMIA:002686-57983 | No, not counted |
| thresher shark | Alopias vulpinus | OMIA:002686-7852 | No, not counted |
| tiger shark | Galeocerdo cuvier | OMIA:002686-7819 | No, not counted |
| tufted capuchin | Sapajus apella | OMIA:002686-9515 | Yes |
| white-tufted-ear marmoset | Callithrix jacchus | OMIA:002686-9483 | Yes |
Genes
Each gene OMIA records for a species entry, and the human gene it reaches through Ensembl's orthologs.
| Species | Animal gene | Human gene | Ortholog |
|---|---|---|---|
| crab-eating macaque | No gene | OMIA records no gene for this species entry. | |
| Japanese medaka | No gene | OMIA records no gene for this species entry. | |
| tufted capuchin | No gene | OMIA records no gene for this species entry. | |
| white-tufted-ear marmoset | No gene | OMIA records no gene for this species entry. | |
| Australian swellshark Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| dusky shark Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| great white shark Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| gummy shark Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| lemon shark Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| Port Jackson shark Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| shortfin mako shark Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| thresher shark Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| tiger shark Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
Human diseases
Two routes lead from an OMIA group to a Mondo human disease: OMIA's own Mondo link, and the group's OMIM numbers through Mondo's cross-references.
- OMIA's own Mondo link: found a disease.
- OMIA's OMIM numbers: found a disease.
The two routes found different diseases. OMIA's own link is broader: its disease is a parent of one the OMIM numbers found.
| Mondo disease | Name | Found by |
|---|---|---|
| MONDO:0001703 | color vision disorder The absence of or defect in the perception of colors. | OMIA's own Mondo link |
| MONDO:0010564 | red-green color blindness Deuteranopia is a type of color vision deficiency where the green photoreceptors are absent. It affects hue discrimination in the same way as protanopia, but without the dimming effect. Like protanopia, it is hereditary, sex-linked, and found in about 1% of the male population. | OMIA's OMIM numbers |
Target evidence
Each Open Targets association between one of the group's human genes and one of its human diseases, with its overall score and the score for each kind of evidence.
The chain did not reach target evidence.
Drugs
The chain did not reach the drugs.