OMIA group 2997
Chromosomal structural anomaly, translocation, centric fusion
The chain
From the animal disease to the drugs. The page shows what each step found and where the chain stopped. It does not say whether the animal is a model of a human disease.
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Animal disease
Reached
OMIA records it in 17 species entries marked as a defect.
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Human disease
Stopped here
Neither OMIA's own Mondo link nor its OMIM numbers lead to a Mondo disease.
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Human gene
Not reached
The chain stopped before this step.
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Target evidence
Not reached
The chain stopped before this step.
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Drugs
Not reached
The chain stopped before this step.
The chain stopped at Human disease: Neither OMIA's own Mondo link nor its OMIM numbers lead to a Mondo disease.
Natural-model score
How complete and how well supported the chain to each human disease is, out of 100, by stated rules. It does not say that the animal is a validated model of the human disease. How the score works.
This group reaches no human disease, so it has no score.
Species
The chain follows only the species entries that OMIA marks as a defect.
| Species | Scientific name | OMIA entry | A defect |
|---|---|---|---|
| American beaver | Castor canadensis | OMIA:002997-51338 | Yes |
| Arabian oryx | Oryx leucoryx | OMIA:002997-39411 | Yes |
| Arctic fox | Vulpes lagopus | OMIA:002997-494514 | Yes |
| Atlantic cod | Gadus morhua | OMIA:002997-8049 | Yes |
| dog | Canis lupus familiaris | OMIA:002997-9615 | Yes |
| domestic cattle | Bos taurus | OMIA:002997-9913 | Unknown, not counted |
| domestic guinea pig | Cavia porcellus | OMIA:002997-10141 | Unknown, not counted |
| Eurasian beaver | Castor fiber | OMIA:002997-10185 | Yes |
| European plaice | Pleuronectes platessa | OMIA:002997-8262 | Yes |
| European shrew | Sorex araneus | OMIA:002997-42254 | Yes |
| goat | Capra hircus | OMIA:002997-9925 | Yes |
| horse | Equus caballus | OMIA:002997-9796 | Yes |
| pig | Sus scrofa | OMIA:002997-9823 | Yes |
| pink salmon | Oncorhynchus gorbuscha | OMIA:002997-8017 | Yes |
| rabbit | Oryctolagus cuniculus | OMIA:002997-9986 | Yes |
| raccoon dog | Nyctereutes procyonoides | OMIA:002997-34880 | Yes |
| river trout | Salmo trutta | OMIA:002997-8032 | Yes |
| rock goby | Gobius paganellus | OMIA:002997-85418 | Yes |
| sheep | Ovis aries | OMIA:002997-9940 | Yes |
Genes
Each gene OMIA records for a species entry, and the human gene it reaches through Ensembl's orthologs.
| Species | Animal gene | Human gene | Ortholog |
|---|---|---|---|
| American beaver | No gene | OMIA records no gene for this species entry. | |
| Arabian oryx | No gene | OMIA records no gene for this species entry. | |
| Arctic fox | No gene | OMIA records no gene for this species entry. | |
| Atlantic cod | No gene | OMIA records no gene for this species entry. | |
| dog | No gene | OMIA records no gene for this species entry. | |
| Eurasian beaver | No gene | OMIA records no gene for this species entry. | |
| European plaice | No gene | OMIA records no gene for this species entry. | |
| European shrew | No gene | OMIA records no gene for this species entry. | |
| goat | No gene | OMIA records no gene for this species entry. | |
| horse | No gene | OMIA records no gene for this species entry. | |
| pig | No gene | OMIA records no gene for this species entry. | |
| pink salmon | No gene | OMIA records no gene for this species entry. | |
| rabbit | No gene | OMIA records no gene for this species entry. | |
| raccoon dog | No gene | OMIA records no gene for this species entry. | |
| river trout | No gene | OMIA records no gene for this species entry. | |
| rock goby | No gene | OMIA records no gene for this species entry. | |
| sheep | No gene | OMIA records no gene for this species entry. | |
| domestic cattle Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| domestic guinea pig Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
Human diseases
Two routes lead from an OMIA group to a Mondo human disease: OMIA's own Mondo link, and the group's OMIM numbers through Mondo's cross-references.
- OMIA's own Mondo link: OMIA links the group to no Mondo disease.
- OMIA's OMIM numbers: OMIA gives the group no OMIM number marked as a trait.
The chain did not reach a human disease.
Target evidence
Each Open Targets association between one of the group's human genes and one of its human diseases, with its overall score and the score for each kind of evidence.
The chain did not reach target evidence.
Drugs
The chain did not reach the drugs.