OMIA group 439
Hair, long
The chain
From the animal disease to the drugs. The page shows what each step found and where the chain stopped. It does not say whether the animal is a model of a human disease.
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Animal disease
Reached
OMIA records it in 1 species entry marked as a defect.
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Human disease
Reached
1 Mondo disease.
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Human gene
Stopped here
No gene of a species entry marked as a defect reaches a human gene through Ensembl's orthologs.
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Target evidence
Not reached
The chain stopped before this step.
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Drugs
Not reached
The chain stopped before this step.
The chain stopped at Human gene: No gene of a species entry marked as a defect reaches a human gene through Ensembl's orthologs.
Natural-model score
How complete and how well supported the chain to each human disease is, out of 100, by stated rules. It does not say that the animal is a validated model of the human disease. How the score works.
14.0 out of 100
| Part | Computed from | Points |
|---|---|---|
| Target evidence | No Open Targets association with this disease | 0.0 of 35 |
| Drugs | No drug has been tested for this disease, and none acts on its genes | 0.0 of 25 |
| Ortholog | No gene of a naturally occurring entry reaches a human gene | 0.0 of 20 |
| Both routes | Both routes found this disease | 10.0 of 10 |
| Species | 1 naturally occurring species entry marked as a defect | 4.0 of 10 |
Species
The chain follows only the species entries that OMIA marks as a defect.
| Species | Scientific name | OMIA entry | A defect |
|---|---|---|---|
| alpaca | Vicugna pacos | OMIA:000439-30538 | No, not counted |
| Arabian camel | Camelus dromedarius | OMIA:000439-9838 | No, not counted |
| dog | Canis lupus familiaris | OMIA:000439-9615 | No, not counted |
| domestic cat | Felis catus | OMIA:000439-9685 | No, not counted |
| domestic cattle | Bos taurus | OMIA:000439-9913 | No, not counted |
| domestic guinea pig | Cavia porcellus | OMIA:000439-10141 | No, not counted |
| domestic yak | Bos grunniens | OMIA:000439-30521 | No, not counted |
| donkey | Equus asinus | OMIA:000439-9793 | No, not counted |
| goat Naturally occurring, and also genetically engineered. | Capra hircus | OMIA:000439-9925 | No, not counted |
| golden hamster | Mesocricetus auratus | OMIA:000439-10036 | Yes |
| llama | Lama glama | OMIA:000439-9844 | No, not counted |
| rabbit | Oryctolagus cuniculus | OMIA:000439-9986 | No, not counted |
| sheep Genetically engineered, not naturally occurring. Not counted in the score. | Ovis aries | OMIA:000439-9940 | No, not counted |
Genes
Each gene OMIA records for a species entry, and the human gene it reaches through Ensembl's orthologs.
| Species | Animal gene | Human gene | Ortholog |
|---|---|---|---|
| golden hamster | Fgf5 fibroblast growth factor 5 NCBI Gene 101828257 | Ensembl does not know this NCBI Gene identifier. | |
| alpaca Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| Arabian camel Not a defect, not counted | FGF5 fibroblast growth factor 5 NCBI Gene 105091789 | Ensembl does not know this NCBI Gene identifier. | |
| dog Not a defect, not counted | FGF5 fibroblast growth factor 5 NCBI Gene 608459 | FGF5 Ensembl | one to one |
| domestic cat Not a defect, not counted | FGF5 fibroblast growth factor 5 NCBI Gene 100136904 | Ensembl does not know this NCBI Gene identifier. | |
| domestic cattle Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| domestic guinea pig Not a defect, not counted | Fgf5 fibroblast growth factor 5 NCBI Gene 100722934 | FGF5 Ensembl | one to one |
| domestic yak Not a defect, not counted | No gene | OMIA records no gene for this species entry. | |
| donkey Not a defect, not counted | FGF5 fibroblast growth factor 5 NCBI Gene 106828064 | FGF5 Ensembl | one to one |
| goat Not a defect, not counted | FGF5 fibroblast growth factor 5 NCBI Gene 100861298 | Ensembl does not know this NCBI Gene identifier. | |
| llama Not a defect, not counted | FGF5 | No NCBI Gene identifier in OMIA. | |
| rabbit Not a defect, not counted | FGF5 fibroblast growth factor 5 NCBI Gene 100316906 | FGF5 Ensembl | one to one |
| sheep Not a defect, not counted | FGF5 fibroblast growth factor 5 NCBI Gene 100642180 | FGF5 Ensembl | one to one |
Human diseases
Two routes lead from an OMIA group to a Mondo human disease: OMIA's own Mondo link, and the group's OMIM numbers through Mondo's cross-references.
- OMIA's own Mondo link: found a disease.
- OMIA's OMIM numbers: found a disease.
| Mondo disease | Name | Found by |
|---|---|---|
| MONDO:0008593 | trichomegaly | Both routes |
Target evidence
Each Open Targets association between one of the group's human genes and one of its human diseases, with its overall score and the score for each kind of evidence.
The chain did not reach target evidence.
Drugs
The chain did not reach the drugs.