Human disease
essential hypertension
Mondo defines it as: “Hypertension that presents without an identifiable cause.”
1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 510 | Hypertension, essential | The group's name | 1 | Human disease |
31.5
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
Open Targets links none of these groups' human genes to this disease.
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Hydrochlorothiazide | None of these genes | Approved |
| Mecamylamine | None of these genes | Approved |
| Seractide Acetate | None of these genes | Approved |
| Spironolactone | None of these genes | Approved |
| Telmisartan | None of these genes | Approved |
| Aliskiren | None of these genes | Phase 3 |
| Amlodipine | None of these genes | Phase 3 |
| Atorvastatin | None of these genes | Phase 3 |
| Azelnidipine | None of these genes | Phase 3 |
| Azilsartan | None of these genes | Phase 3 |
| Azilsartan Medoxomil | None of these genes | Phase 3 |
| Benazepril | None of these genes | Phase 3 |
| Bisoprolol | None of these genes | Phase 3 |
| Candesartan | None of these genes | Phase 3 |
| Candesartan Cilexetil | None of these genes | Phase 3 |
| Captopril | None of these genes | Phase 3 |
| Carvedilol | None of these genes | Phase 3 |
| Chlorothiazide | None of these genes | Phase 3 |
| Chlorthalidone | None of these genes | Phase 3 |
| Dapagliflozin | None of these genes | Phase 3 |
| Drospirenone | None of these genes | Phase 3 |
| Enalapril | None of these genes | Phase 3 |
| Eplerenone | None of these genes | Phase 3 |
| Eprosartan | None of these genes | Phase 3 |
| Estradiol | None of these genes | Phase 3 |
| Ezetimibe | None of these genes | Phase 3 |
| Fimasartan | None of these genes | Phase 3 |
| Indapamide | None of these genes | Phase 3 |
| Irbesartan | None of these genes | Phase 3 |
| Lercanidipine | None of these genes | Phase 3 |
| Levamlodipine | None of these genes | Phase 3 |
| Lisinopril Anhydrous | None of these genes | Phase 3 |
| Losartan | None of these genes | Phase 3 |
| Metoprolol | None of these genes | Phase 3 |
| Moxonidine | None of these genes | Phase 3 |
| Nebivolol | None of these genes | Phase 3 |
| Nifedipine | None of these genes | Phase 3 |
| Olmesartan | None of these genes | Phase 3 |
| Olmesartan Medoxomil | None of these genes | Phase 3 |
| Perindopril | None of these genes | Phase 3 |
| Rauwolfia Serpentina | None of these genes | Phase 3 |
| Rosuvastatin | None of these genes | Phase 3 |
| Sacubitril | None of these genes | Phase 3 |
| Simvastatin | None of these genes | Phase 3 |
| Sitokiren | None of these genes | Phase 3 |
| Topiramate | None of these genes | Phase 3 |
| Torsemide | None of these genes | Phase 3 |
| Valsartan | None of these genes | Phase 3 |
| Xl550 | None of these genes | Phase 3 |
| Arginine | None of these genes | Phase 2/3 |
| Bexagliflozin | None of these genes | Phase 2/3 |
| Act-280778 | None of these genes | Phase 2 |
| Allopurinol | None of these genes | Phase 2 |
| Aprocitentan | None of these genes | Phase 2 |
| Firibastat | None of these genes | Phase 2 |
| Melatonin | None of these genes | Phase 2 |
| Osilodrostat | None of these genes | Phase 2 |
| Pf-00489791 | None of these genes | Phase 2 |
| Rostafuroxin | None of these genes | Phase 2 |
| Magnesium | None of these genes | Phase 1/2 |
| Magnesium Citrate | None of these genes | Phase 1/2 |
| Cocoa | None of these genes | Phase 1 |
| Fenoldopam | None of these genes | Phase 1 |
| Naproxcinod | None of these genes | Phase 1 |
| Naproxen | None of these genes | Phase 1 |
| Talfirastide | None of these genes | Phase 1 |
| Bifidobacterium Spp. | None of these genes | Early phase 1 |
| Amiloride | None of these genes | Unknown |
| Atenolol | None of these genes | Unknown |
| Bq-123 | None of these genes | Unknown |
| Bq 788 | None of these genes | Unknown |
| Febuxostat | None of these genes | Unknown |
| Felodipine | None of these genes | Unknown |
| Lacidipine | None of these genes | Unknown |
| Oxytocin | None of these genes | Unknown |
| Ramipril | None of these genes | Unknown |
| Rasburicase | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.