Human disease
hypogonadism
Mondo defines it as: “A disorder characterized by decreased function of the gonads. Clinical manifestations in both males and females include poor libido, infertility, and osteoporosis. Additional signs in males include erectile dysfunction, muscle atrophy, gynecomastia and increased abdominal fat. In females, additional signs include shrinking of the breasts and loss of, or failure to develop menstruation.”
1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 522 | Hypogonadism | The group's name | 2 | Human disease |
34.5
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
Open Targets links none of these groups' human genes to this disease.
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Bromocriptine | None of these genes | Approved |
| Choriogonadotropin Alfa | None of these genes | Approved |
| Estradiol | None of these genes | Approved |
| Estradiol Valerate | None of these genes | Approved |
| Estrogens, Conjugated | None of these genes | Approved |
| Estrogens, Esterified | None of these genes | Approved |
| Estrone Sulfuric Acid | None of these genes | Approved |
| Fluoxymesterone | None of these genes | Approved |
| Follitropin | None of these genes | Approved |
| Follitropin Alfa | None of these genes | Approved |
| Follitropin Beta | None of these genes | Approved |
| Methyltestosterone | None of these genes | Approved |
| Norethindrone Acetate | None of these genes | Approved |
| Testosterone | None of these genes | Approved |
| Testosterone Cypionate | None of these genes | Approved |
| Testosterone Enanthate | None of these genes | Approved |
| Testosterone Undecanoate | None of these genes | Approved |
| Albuvirtide | None of these genes | Phase 3 |
| Anakinra | None of these genes | Phase 3 |
| Dutasteride | None of these genes | Phase 3 |
| Enclomiphene | None of these genes | Phase 3 |
| Finasteride | None of these genes | Phase 3 |
| Letrozole | None of these genes | Phase 3 |
| Anastrozole | None of these genes | Phase 2 |
| Clomiphene | None of these genes | Phase 2 |
| Fispemifene | None of these genes | Phase 2 |
| Stanolone | None of these genes | Phase 2 |
| Relugolix | None of these genes | Phase 1/2 |
| Acyline | None of these genes | Phase 1 |
| Degarelix | None of these genes | Phase 1 |
| Estrogen | None of these genes | Unknown |
| Gonadorelin | None of these genes | Unknown |
| Gonadotropin, Chorionic | None of these genes | Unknown |
| Leuprolide | None of these genes | Unknown |
| Progesterone | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.