Human disease
diabetes mellitus
Mondo defines it as: “A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.”
1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 277 | Diabetes | The group's name | 5 | Human disease |
37.5
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
Open Targets links none of these groups' human genes to this disease.
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Acarbose | None of these genes | Approved |
| Acetohexamide | None of these genes | Approved |
| Albiglutide | None of these genes | Approved |
| Alogliptin | None of these genes | Approved |
| Amlodipine | None of these genes | Approved |
| Atenolol | None of these genes | Approved |
| Beinaglutide | None of these genes | Approved |
| Benazepril | None of these genes | Approved |
| Benfluorex | None of these genes | Approved |
| Bexagliflozin | None of these genes | Approved |
| Buformin | None of these genes | Approved |
| Canagliflozin Anhydrous | None of these genes | Approved |
| Candesartan Cilexetil | None of these genes | Approved |
| Carbutamide | None of these genes | Approved |
| Carfloglitazar | None of these genes | Approved |
| Chlorpropamide | None of these genes | Approved |
| Chlorthalidone | None of these genes | Approved |
| Dapagliflozin | None of these genes | Approved |
| Dasiglucagon | None of these genes | Approved |
| Dorzagliatin | None of these genes | Approved |
| Dulaglutide | None of these genes | Approved |
| Duloxetine | None of these genes | Approved |
| Empagliflozin | None of these genes | Approved |
| Enavogliflozin | None of these genes | Approved |
| Ertugliflozin | None of these genes | Approved |
| Evogliptin | None of these genes | Approved |
| Exenatide | None of these genes | Approved |
| Felodipine | None of these genes | Approved |
| Fenofibrate | None of these genes | Approved |
| Gemigliptin | None of these genes | Approved |
| Glibornuride | None of these genes | Approved |
| Gliclazide | None of these genes | Approved |
| Glimepiride | None of these genes | Approved |
| Glipizide | None of these genes | Approved |
| Gliquidone | None of these genes | Approved |
| Glisoxepide | None of these genes | Approved |
| Glucagon | None of these genes | Approved |
| Glyburide | None of these genes | Approved |
| Glymidine | None of these genes | Approved |
| Guar Gum | None of these genes | Approved |
| Hydrochlorothiazide | None of these genes | Approved |
| Imeglimin | None of these genes | Approved |
| Insulin Aspart | None of these genes | Approved |
| Insulin Degludec | None of these genes | Approved |
| Insulin Detemir | None of these genes | Approved |
| Insulin Glargine | None of these genes | Approved |
| Insulin Glulisine | None of these genes | Approved |
| Insulin Human | None of these genes | Approved |
| Insulin Icodec | None of these genes | Approved |
| Insulin Lispro | None of these genes | Approved |
| Insulin Purified Beef | None of these genes | Approved |
| Insulin Purified Pork | None of these genes | Approved |
| Ipragliflozin | None of these genes | Approved |
| Linagliptin | None of these genes | Approved |
| Liraglutide | None of these genes | Approved |
| Lisinopril Anhydrous | None of these genes | Approved |
| Lixisenatide | None of these genes | Approved |
| Lobeglitazone | None of these genes | Approved |
| Luseogliflozin | None of these genes | Approved |
| Metahexamide | None of these genes | Approved |
| Metformin | None of these genes | Approved |
| Miglitol | None of these genes | Approved |
| Mitiglinide | None of these genes | Approved |
| Nateglinide | None of these genes | Approved |
| Olmesartan Medoxomil | None of these genes | Approved |
| Omega-3-Acid Ethyl Esters | None of these genes | Approved |
| Phenformin | None of these genes | Approved |
| Pioglitazone | None of these genes | Approved |
| Pramlintide | None of these genes | Approved |
| Prazosin | None of these genes | Approved |
| Quinapril | None of these genes | Approved |
| Ramipril | None of these genes | Approved |
| Repaglinide | None of these genes | Approved |
| Rosiglitazone | None of these genes | Approved |
| Saxagliptin Anhydrous | None of these genes | Approved |
| Semaglutide | None of these genes | Approved |
| Sitagliptin | None of these genes | Approved |
| Sodium Chloride | None of these genes | Approved |
| Sotagliflozin | None of these genes | Approved |
| Telmisartan | None of these genes | Approved |
| Teneligliptin | None of these genes | Approved |
| Ticagrelor | None of these genes | Approved |
| Tirzepatide | None of these genes | Approved |
| Tolazamide | None of these genes | Approved |
| Tolbutamide | None of these genes | Approved |
| Tolrestat | None of these genes | Approved |
| Troglitazone | None of these genes | Approved |
| Valsartan | None of these genes | Approved |
| Verapamil | None of these genes | Approved |
| Vildagliptin | None of these genes | Approved |
| Voglibose | None of these genes | Approved |
| Aflibercept | None of these genes | Phase 3 |
| Aliskiren | None of these genes | Phase 3 |
| Aloe | None of these genes | Phase 3 |
| Antimony | None of these genes | Phase 3 |
| Atorvastatin | None of these genes | Phase 3 |
| Baricitinib | None of these genes | Phase 3 |
| Basiliximab | None of these genes | Phase 3 |
| Chlorin E6 | None of these genes | Phase 3 |
| Cyclosporine | None of these genes | Phase 3 |
| Evacetrapib | None of these genes | Phase 3 |
| Everolimus | None of these genes | Phase 3 |
| Ezetimibe | None of these genes | Phase 3 |
| Fasiglifam | None of these genes | Phase 3 |
| Gemcitabine | None of these genes | Phase 3 |
| Honey | None of these genes | Phase 3 |
| Inclisiran | None of these genes | Phase 3 |
| Lactobacillus Acidophilus | None of these genes | Phase 3 |
| Melatonin | None of these genes | Phase 3 |
| Metreleptin | None of these genes | Phase 3 |
| Mycophenolic Acid | None of these genes | Phase 3 |
| (+/-)Nicotine | None of these genes | Phase 3 |
| Nicotine | None of these genes | Phase 3 |
| Paclitaxel | None of these genes | Phase 3 |
| Polyethylene Glycol | None of these genes | Phase 3 |
| Remdesivir | None of these genes | Phase 3 |
| Rosuvastatin | None of these genes | Phase 3 |
| Ruboxistaurin | None of these genes | Phase 3 |
| Sildenafil | None of these genes | Phase 3 |
| Simvastatin | None of these genes | Phase 3 |
| Sirolimus | None of these genes | Phase 3 |
| Sodium Fluoride | None of these genes | Phase 3 |
| Tadalafil | None of these genes | Phase 3 |
| Trelagliptin | None of these genes | Phase 3 |
| Triclosan | None of these genes | Phase 3 |
| Tropicamide | None of these genes | Phase 3 |
| Warfarin | None of these genes | Phase 3 |
| Zinc Acetate Anhydrous | None of these genes | Phase 3 |
| Zinc Sulfate | None of these genes | Phase 3 |
| Acetylcysteine | None of these genes | Phase 2/3 |
| Arginine | None of these genes | Phase 2/3 |
| Ascorbic Acid | None of these genes | Phase 2/3 |
| Clazakizumab | None of these genes | Phase 2/3 |
| Deferiprone | None of these genes | Phase 2/3 |
| Ebselen | None of these genes | Phase 2/3 |
| Epigalocatechin Gallate | None of these genes | Phase 2/3 |
| Omega-3 Fatty Acids | None of these genes | Phase 2/3 |
| Acacia | None of these genes | Phase 2 |
| Amoxicillin | None of these genes | Phase 2 |
| Aprepitant | None of these genes | Phase 2 |
| Bifidobacterium Spp. | None of these genes | Phase 2 |
| Bismuth Subcitrate | None of these genes | Phase 2 |
| Bivalirudin | None of these genes | Phase 2 |
| Calcium Carbonate | None of these genes | Phase 2 |
| Cholecalciferol | None of these genes | Phase 2 |
| Clarithromycin | None of these genes | Phase 2 |
| Deferoxamine | None of these genes | Phase 2 |
| Dextrose | None of these genes | Phase 2 |
| Epalrestat | None of these genes | Phase 2 |
| Golocdacimab | None of these genes | Phase 2 |
| Liothyronine | None of these genes | Phase 2 |
| Mirabegron | None of these genes | Phase 2 |
| Naltrexone | None of these genes | Phase 2 |
| Nitric Oxide | None of these genes | Phase 2 |
| Nitrous Acid | None of these genes | Phase 2 |
| Omeprazole | None of these genes | Phase 2 |
| Ondansetron | None of these genes | Phase 2 |
| Pegaptanib Sodium | None of these genes | Phase 2 |
| Pegpleranib Sodium | None of these genes | Phase 2 |
| Phentermine | None of these genes | Phase 2 |
| Pravastatin | None of these genes | Phase 2 |
| Relamorelin | None of these genes | Phase 2 |
| Rimonabant | None of these genes | Phase 2 |
| Runcaciguat | None of these genes | Phase 2 |
| Sevelamer | None of these genes | Phase 2 |
| Sorafenib | None of these genes | Phase 2 |
| Tacrolimus Anhydrous | None of these genes | Phase 2 |
| Tislelizumab | None of these genes | Phase 2 |
| Topiramate | None of these genes | Phase 2 |
| Trazpiroben | None of these genes | Phase 2 |
| Tzp-102 | None of these genes | Phase 2 |
| Vixotrigine | None of these genes | Phase 2 |
| Volanesorsen | None of these genes | Phase 2 |
| Cicletanine | None of these genes | Phase 1/2 |
| Curcumin | None of these genes | Phase 1/2 |
| Darbepoetin Alfa | None of these genes | Phase 1/2 |
| Epoetin Alfa | None of these genes | Phase 1/2 |
| Epoetin Beta | None of these genes | Phase 1/2 |
| Glycopyrronium | None of these genes | Phase 1/2 |
| Itopride | None of these genes | Phase 1/2 |
| Magnesium | None of these genes | Phase 1/2 |
| Perhexiline | None of these genes | Phase 1/2 |
| Proglumide | None of these genes | Phase 1/2 |
| Pyridostigmine | None of these genes | Phase 1/2 |
| Trc-150094 | None of these genes | Phase 1/2 |
| Alemtuzumab | None of these genes | Phase 1 |
| Carbidopa Anhydrous | None of these genes | Phase 1 |
| Ecnoglutide | None of these genes | Phase 1 |
| Fluconazole | None of these genes | Phase 1 |
| Hyaluronic Acid | None of these genes | Phase 1 |
| Hyaluronidase (Human Recombinant) | None of these genes | Phase 1 |
| Indocyanine Green Acid Form | None of these genes | Phase 1 |
| Insulin Peglispro | None of these genes | Phase 1 |
| Levodopa | None of these genes | Phase 1 |
| Minocycline | None of these genes | Phase 1 |
| Rifampin | None of these genes | Phase 1 |
| Ursodiol | None of these genes | Phase 1 |
| Atropine | None of these genes | Early phase 1 |
| Avexitide | None of these genes | Early phase 1 |
| Berberine | None of these genes | Early phase 1 |
| Edetic Acid | None of these genes | Early phase 1 |
| Adomeglivant | None of these genes | Unknown |
| Alprostadil | None of these genes | Unknown |
| Angiotensin Ii | None of these genes | Unknown |
| Angiotensin-Ii | None of these genes | Unknown |
| Azilsartan | None of these genes | Unknown |
| Bepotastine | None of these genes | Unknown |
| Bisoprolol | None of these genes | Unknown |
| Bupivacaine | None of these genes | Unknown |
| Cadisegliatin | None of these genes | Unknown |
| Carvedilol | None of these genes | Unknown |
| Dexamethasone | None of these genes | Unknown |
| Doxycycline Anhydrous | None of these genes | Unknown |
| Efpeglenatide | None of these genes | Unknown |
| Eloralintide | None of these genes | Unknown |
| Eplerenone | None of these genes | Unknown |
| Ergocalciferol | None of these genes | Unknown |
| Ertapenem | None of these genes | Unknown |
| Estrogen | None of these genes | Unknown |
| Homatropine | None of these genes | Unknown |
| Hydrocortisone | None of these genes | Unknown |
| Icovamenib | None of these genes | Unknown |
| Insulin Human, Isophane | None of these genes | Unknown |
| Lactulose | None of these genes | Unknown |
| Lidocaine | None of these genes | Unknown |
| Lipoic Acid, Alpha | None of these genes | Unknown |
| Lotiglipron | None of these genes | Unknown |
| Mazdutide | None of these genes | Unknown |
| Mepivacaine | None of these genes | Unknown |
| Methylphenidate | None of these genes | Unknown |
| Methylprednisolone | None of these genes | Unknown |
| Metoprolol | None of these genes | Unknown |
| Molgramostim | None of these genes | Unknown |
| Neomycin | None of these genes | Unknown |
| Nisotirostide | None of these genes | Unknown |
| Norepinephrine | None of these genes | Unknown |
| Olatorepatide | None of these genes | Unknown |
| Oxygen | None of these genes | Unknown |
| Oxytocin | None of these genes | Unknown |
| Polymyxin B | None of these genes | Unknown |
| Propofol | None of these genes | Unknown |
| Propolis Wax | None of these genes | Unknown |
| Propranolol | None of these genes | Unknown |
| Protamine Sulfate | None of these genes | Unknown |
| Regramostim | None of these genes | Unknown |
| Resveratrol | None of these genes | Unknown |
| Retatrutide | None of these genes | Unknown |
| Rocuronium | None of these genes | Unknown |
| Sargramostim | None of these genes | Unknown |
| Sevoflurane | None of these genes | Unknown |
| Terbinafine | None of these genes | Unknown |
| Testosterone | None of these genes | Unknown |
| Tranexamic Acid | None of these genes | Unknown |
| Volagidemab | None of these genes | Unknown |
| Water | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.