Comparative

Human disease

osteoporosis

MONDO:0005298

Mondo defines it as: “A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss).”

1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.

Animal diseases

By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.

OMIA group Name Found by Species The chain reached Score
105 Osteoporosis The group's name 1 Human disease 31.5

Human genes

Each human gene of these disease groups that Open Targets links to this disease.

Open Targets links none of these groups' human genes to this disease.

Drugs tested for this disease

Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.

Drug Acts on Latest stage for this disease
Abaloparatide None of these genes Approved
Alendronic Acid None of these genes Approved
Bazedoxifene None of these genes Approved
Calcitonin None of these genes Approved
Calcium None of these genes Approved
Calcium Carbonate None of these genes Approved
Cholecalciferol None of these genes Approved
Cyanocobalamin None of these genes Approved
Denosumab None of these genes Approved
Eldecalcitol None of these genes Approved
Estradiol None of these genes Approved
Estrogens, Conjugated None of these genes Approved
Estrogens, Conjugated Synthetic A None of these genes Approved
Estrone Sulfuric Acid None of these genes Approved
Etidronic Acid None of these genes Approved
Folic Acid None of these genes Approved
Ibandronic Acid None of these genes Approved
Ipriflavone None of these genes Approved
Lasofoxifene None of these genes Approved
Levonorgestrel None of these genes Approved
Minodronic Acid None of these genes Approved
Nandrolone None of these genes Approved
Pyridoxine None of these genes Approved
Raloxifene None of these genes Approved
Risedronic Acid None of these genes Approved
Romosozumab None of these genes Approved
Smc021 None of these genes Approved
Sodium Fluoride None of these genes Approved
Strontium Ranelate None of these genes Approved
Teriparatide None of these genes Approved
Teriparatide Acetate None of these genes Approved
Testosterone None of these genes Approved
Tiludronic Acid None of these genes Approved
Zoledronic Acid Anhydrous None of these genes Approved
Arzoxifene None of these genes Phase 3
Calcitonin Salmon None of these genes Phase 3
Cinacalcet None of these genes Phase 3
Clodronic Acid None of these genes Phase 3
Ergocalciferol None of these genes Phase 3
Estrogen None of these genes Phase 3
Isosorbide Mononitrate None of these genes Phase 3
Menatetrenone None of these genes Phase 3
Nitroglycerin None of these genes Phase 3
Odanacatib None of these genes Phase 3
Parathyroid Hormone None of these genes Phase 3
Progesterone None of these genes Phase 3
Sitagliptin None of these genes Phase 3
Somatropin None of these genes Phase 3
Genistein None of these genes Phase 2/3
Phytonadione None of these genes Phase 2/3
Alfacalcidol None of these genes Phase 2
Balicatib None of these genes Phase 2
Blosozumab None of these genes Phase 2
Calcitriol None of these genes Phase 2
Calcium Phosphate, Dibasic None of these genes Phase 2
Calcium Phosphate, Tribasic None of these genes Phase 2
Dasatinib Anhydrous None of these genes Phase 2
Deferasirox None of these genes Phase 2
Dp001 None of these genes Phase 2
Encaleret None of these genes Phase 2
Evatanepag None of these genes Phase 2
Fluoride None of these genes Phase 2
Magnesium None of these genes Phase 2
Mk-0773 None of these genes Phase 2
Narlumosbart None of these genes Phase 2
Neridronic Acid None of these genes Phase 2
Nicotinamide Riboside None of these genes Phase 2
Ono-5334 None of these genes Phase 2
Ostabolin-C None of these genes Phase 2
Quercetin None of these genes Phase 2
Ronacaleret None of these genes Phase 2
Rosiglitazone None of these genes Phase 2
Rosuvastatin None of these genes Phase 2
Sb-423562 None of these genes Phase 2
Semparatide None of these genes Phase 2
Sodium Chloride None of these genes Phase 2
Sodium Pentaborate Pentahydrate None of these genes Phase 2
Tamoxifen None of these genes Phase 2
Apomine None of these genes Phase 1/2
Bifidobacterium Spp. None of these genes Phase 1/2
Pamidronic Acid None of these genes Phase 1/2
Rivogenlecleucel None of these genes Phase 1/2
Amg-167 None of these genes Phase 1
Atf-936 None of these genes Phase 1
Axt-914 None of these genes Phase 1
Chf4227 None of these genes Phase 1
Lgd-2941 None of these genes Phase 1
Relacatib None of these genes Phase 1
Resugosbart None of these genes Phase 1
Diphyllin None of these genes Investigational new drug
Rad-140 None of these genes Investigational new drug
Benzenesulfonamide None of these genes Preclinical
Bemiparin None of these genes Unknown
Calcium Lactate None of these genes Unknown
Dalteparin Sodium None of these genes Unknown
Daniplestim None of these genes Unknown
Dibotermin Alfa None of these genes Unknown
Enoxaparin None of these genes Unknown
Enoxaparin Sodium None of these genes Unknown
Heparin None of these genes Unknown
Heparin Calcium None of these genes Unknown
Heparin Sodium None of these genes Unknown
Ibuprofen None of these genes Unknown
Letrozole None of these genes Unknown
Mecasermin None of these genes Unknown
Menaquinone None of these genes Unknown
Nadroparin Calcium None of these genes Unknown
Norethindrone Acetate None of these genes Unknown
Testosterone Undecanoate None of these genes Unknown
Tinzaparin None of these genes Unknown
Tinzaparin Sodium None of these genes Unknown

The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.