Human disease
systemic lupus erythematosus
Mondo defines it as: “An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.”
1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 968 | Systemic lupus erythematosus | OMIA's OMIM numbers | 2 | Human disease |
37.0
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
Open Targets links none of these groups' human genes to this disease.
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Anifrolumab | None of these genes | Approved |
| Belimumab | None of these genes | Approved |
| Cortisone Acetate | None of these genes | Approved |
| Dexamethasone | None of these genes | Approved |
| Dexamethasone Phosphoric Acid | None of these genes | Approved |
| Hydroxychloroquine | None of these genes | Approved |
| Prednisolone | None of these genes | Approved |
| Prednisone | None of these genes | Approved |
| Abetimus Sodium | None of these genes | Phase 3 |
| Aldesleukin | None of these genes | Phase 3 |
| Azathioprine | None of these genes | Phase 3 |
| Baricitinib | None of these genes | Phase 3 |
| Blisibimod | None of these genes | Phase 3 |
| Cenerimod | None of these genes | Phase 3 |
| Cholecalciferol | None of these genes | Phase 3 |
| Cravacitinib | None of these genes | Phase 3 |
| Cyclophosphamide Anhydrous | None of these genes | Phase 3 |
| Dapirolizumab Pegol | None of these genes | Phase 3 |
| Epratuzumab | None of these genes | Phase 3 |
| Estrogen | None of these genes | Phase 3 |
| Estrogens, Conjugated | None of these genes | Phase 3 |
| Folic Acid | None of these genes | Phase 3 |
| Forigerimod | None of these genes | Phase 3 |
| Ianalumab | None of these genes | Phase 3 |
| Ibuprofen | None of these genes | Phase 3 |
| Laquinimod | None of these genes | Phase 3 |
| Lenalidomide | None of these genes | Phase 3 |
| Litifilimab | None of these genes | Phase 3 |
| Medroxyprogesterone Acetate | None of these genes | Phase 3 |
| Methotrexate | None of these genes | Phase 3 |
| Methylprednisolone | None of these genes | Phase 3 |
| Mycophenolate Mofetil | None of these genes | Phase 3 |
| Mycophenolic Acid | None of these genes | Phase 3 |
| Nipocalimab | None of these genes | Phase 3 |
| Obinutuzumab | None of these genes | Phase 3 |
| Ocrelizumab | None of these genes | Phase 3 |
| Prasterone | None of these genes | Phase 3 |
| Rituximab | None of these genes | Phase 3 |
| Sirolimus | None of these genes | Phase 3 |
| Tabalumab | None of these genes | Phase 3 |
| Telitacicept | None of these genes | Phase 3 |
| Upadacitinib | None of these genes | Phase 3 |
| Ustekinumab | None of these genes | Phase 3 |
| Atacicept | None of these genes | Phase 2/3 |
| Atorvastatin | None of these genes | Phase 2/3 |
| Infliximab | None of these genes | Phase 2/3 |
| Ramipril | None of these genes | Phase 2/3 |
| 2-(Aminomethyl)Phenol | None of these genes | Phase 2 |
| Abacavir | None of these genes | Phase 2 |
| Abatacept | None of these genes | Phase 2 |
| Abrocitinib | None of these genes | Phase 2 |
| Acazicolcept | None of these genes | Phase 2 |
| Acetylcysteine | None of these genes | Phase 2 |
| Afimetoran | None of these genes | Phase 2 |
| Amg-557 | None of these genes | Phase 2 |
| Antilymphocyte Immunoglobulin (Horse) | None of these genes | Phase 2 |
| Arsenic Trioxide | None of these genes | Phase 2 |
| Artenimol | None of these genes | Phase 2 |
| Betamethasone | None of these genes | Phase 2 |
| Betamethasone Phosphoric Acid | None of these genes | Phase 2 |
| Blinatumomab | None of these genes | Phase 2 |
| Bortezomib | None of these genes | Phase 2 |
| Branebrutinib | None of these genes | Phase 2 |
| Brentuximab Vedotin | None of these genes | Phase 2 |
| Brepocitinib | None of these genes | Phase 2 |
| Curcumin | None of these genes | Phase 2 |
| Cytarabine | None of these genes | Phase 2 |
| Daratumumab | None of these genes | Phase 2 |
| Daxdilimab | None of these genes | Phase 2 |
| Dazukibart | None of these genes | Phase 2 |
| Edratide | None of these genes | Phase 2 |
| Efavaleukin Alfa | None of these genes | Phase 2 |
| Elasomeran | None of these genes | Phase 2 |
| Elsubrutinib | None of these genes | Phase 2 |
| Enpatoran | None of these genes | Phase 2 |
| Envudeucitinib | None of these genes | Phase 2 |
| Evobrutinib | None of these genes | Phase 2 |
| Fenebrutinib | None of these genes | Phase 2 |
| Filgotinib | None of these genes | Phase 2 |
| Filgrastim | None of these genes | Phase 2 |
| Fludarabine | None of these genes | Phase 2 |
| Fostamatinib | None of these genes | Phase 2 |
| Frexalimab | None of these genes | Phase 2 |
| Fulvestrant | None of these genes | Phase 2 |
| Ganciclovir | None of these genes | Phase 2 |
| Human Immunoglobulin G | None of these genes | Phase 2 |
| Hydrocortisone | None of these genes | Phase 2 |
| Iberdomide | None of these genes | Phase 2 |
| Inebilizumab | None of these genes | Phase 2 |
| Interferon Alfa-2b Kinoid | None of these genes | Phase 2 |
| Iscalimab | None of these genes | Phase 2 |
| Lamivudine | None of these genes | Phase 2 |
| Lanraplenib | None of these genes | Phase 2 |
| Leflunomide | None of these genes | Phase 2 |
| Lenabasum | None of these genes | Phase 2 |
| Lenograstim | None of these genes | Phase 2 |
| Levosalbutamol | None of these genes | Phase 2 |
| Lulizumab Pegol | None of these genes | Phase 2 |
| Lumrotatug | None of these genes | Phase 2 |
| Mosunetuzumab | None of these genes | Phase 2 |
| Narsoplimab | None of these genes | Phase 2 |
| Nelfinavir | None of these genes | Phase 2 |
| Niacinamide | None of these genes | Phase 2 |
| Obecabtagene Autoleucel | None of these genes | Phase 2 |
| Obexelimab | None of these genes | Phase 2 |
| Orelabrutinib | None of these genes | Phase 2 |
| Pacibekitug | None of these genes | Phase 2 |
| Paquinimod | None of these genes | Phase 2 |
| Pegfilgrastim | None of these genes | Phase 2 |
| Piperine | None of these genes | Phase 2 |
| R-333 | None of these genes | Phase 2 |
| Rapcabtagene Autoleucel | None of these genes | Phase 2 |
| Rezpegaldesleukin | None of these genes | Phase 2 |
| Rontalizumab | None of these genes | Phase 2 |
| Rosuvastatin | None of these genes | Phase 2 |
| Rozibafusp Alfa | None of these genes | Phase 2 |
| Rslv-132 | None of these genes | Phase 2 |
| Sifalimumab | None of these genes | Phase 2 |
| Solcitinib | None of these genes | Phase 2 |
| Sulfasalazine | None of these genes | Phase 2 |
| Tgn-1412 | None of these genes | Phase 2 |
| Tozinameran | None of these genes | Phase 2 |
| Triamcinolone | None of these genes | Phase 2 |
| Ubidecarenone | None of these genes | Phase 2 |
| Valziflocept | None of these genes | Phase 2 |
| Veltuzumab | None of these genes | Phase 2 |
| Venanprubart | None of these genes | Phase 2 |
| Vobarilizumab | None of these genes | Phase 2 |
| Voclosporin | None of these genes | Phase 2 |
| Zolacabtagene Autoleucel | None of these genes | Phase 2 |
| Aminolevulinic Acid | None of these genes | Phase 1/2 |
| Apg-2575 | None of these genes | Phase 1/2 |
| Avizakimab | None of these genes | Phase 1/2 |
| Budoprutug | None of these genes | Phase 1/2 |
| Clopidogrel | None of these genes | Phase 1/2 |
| Fludarabine Phosphate | None of these genes | Phase 1/2 |
| Ketamine | None of these genes | Phase 1/2 |
| Lipoic Acid, Alpha | None of these genes | Phase 1/2 |
| Methylprednisolone Acetate | None of these genes | Phase 1/2 |
| Naltrexone | None of these genes | Phase 1/2 |
| Pioglitazone | None of these genes | Phase 1/2 |
| Resecabtagene Autoleucel | None of these genes | Phase 1/2 |
| Tacrolimus Anhydrous | None of these genes | Phase 1/2 |
| Tafasitamab | None of these genes | Phase 1/2 |
| Thioctic Acid | None of these genes | Phase 1/2 |
| Tofacitinib | None of these genes | Phase 1/2 |
| Zetomipzomib | None of these genes | Phase 1/2 |
| Ab-101 | None of these genes | Phase 1 |
| Alemtuzumab | None of these genes | Phase 1 |
| Alnuctamab | None of these genes | Phase 1 |
| Amg-811 | None of these genes | Phase 1 |
| Amiselimod | None of these genes | Phase 1 |
| Arundine | None of these genes | Phase 1 |
| Aspirin | None of these genes | Phase 1 |
| Belumosudil | None of these genes | Phase 1 |
| Bendamustine | None of these genes | Phase 1 |
| Biib-068 | None of these genes | Phase 1 |
| Busulfan | None of these genes | Phase 1 |
| Cd40 Ligand | None of these genes | Phase 1 |
| Cizutamig | None of these genes | Phase 1 |
| Cyclosporine | None of these genes | Phase 1 |
| Divozilimab | None of these genes | Phase 1 |
| Felzartamab | None of these genes | Phase 1 |
| Glpg-3970 | None of these genes | Phase 1 |
| Glpg3970 | None of these genes | Phase 1 |
| Gusacitinib | None of these genes | Phase 1 |
| Imvotamab | None of these genes | Phase 1 |
| Itolizumab | None of these genes | Phase 1 |
| Medi-570 | None of these genes | Phase 1 |
| Meloxicam | None of these genes | Phase 1 |
| Mezagitamab | None of these genes | Phase 1 |
| Milatuzumab | None of these genes | Phase 1 |
| Msc-2364447 | None of these genes | Phase 1 |
| Nivolumab | None of these genes | Phase 1 |
| Nnc0114-0006 | None of these genes | Phase 1 |
| Omalizumab | None of these genes | Phase 1 |
| Rimiducid | None of these genes | Phase 1 |
| Sirukumab | None of these genes | Phase 1 |
| Surovatamig | None of these genes | Phase 1 |
| Talacotuzumab | None of these genes | Phase 1 |
| Tocilizumab | None of these genes | Phase 1 |
| Tru-015 | None of these genes | Phase 1 |
| Venetoclax | None of these genes | Phase 1 |
| Vunakizumab | None of these genes | Phase 1 |
| Zimlovisertib | None of these genes | Phase 1 |
| Ezetimibe | None of these genes | Early phase 1 |
| Inaticabtagene Autoleucel | None of these genes | Early phase 1 |
| Influenza Virus Vaccine | None of these genes | Early phase 1 |
| Simvastatin | None of these genes | Early phase 1 |
| Betamethasone Dipropionate | None of these genes | Unknown |
| Calcium | None of these genes | Unknown |
| Duloxetine | None of these genes | Unknown |
| Enoxaparin | None of these genes | Unknown |
| Equecabtagene Autoleucel | None of these genes | Unknown |
| Ergocalciferol | None of these genes | Unknown |
| Estradiol | None of these genes | Unknown |
| Ethinyl Estradiol | None of these genes | Unknown |
| Memantine | None of these genes | Unknown |
| Modafinil | None of these genes | Unknown |
| Norethindrone | None of these genes | Unknown |
| Selenium | None of these genes | Unknown |
| Triamcinolone Acetonide | None of these genes | Unknown |
| Triamcinolone Hexacetonide | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.