Human disease
obsessive-compulsive disorder
Mondo defines it as: “A disorder characterized by the presence of persistent and recurrent irrational thoughts (obsessions), resulting in marked anxiety and repetitive excessive behaviors (compulsions) as a way to try to decrease that anxiety.”
1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 1530 | Compulsive disorder | OMIA's OMIM numbers | 1 | Human disease |
34.0
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
Open Targets links none of these groups' human genes to this disease.
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Clomipramine | None of these genes | Approved |
| Fluoxetine | None of these genes | Approved |
| Fluvoxamine | None of these genes | Approved |
| Paroxetine | None of these genes | Approved |
| Sertraline | None of these genes | Approved |
| Cycloserine | None of these genes | Phase 3 |
| Escitalopram | None of these genes | Phase 3 |
| Human Immunoglobulin G | None of these genes | Phase 3 |
| Memantine | None of these genes | Phase 3 |
| Quetiapine | None of these genes | Phase 3 |
| Serotonin | None of these genes | Phase 3 |
| Topiramate | None of these genes | Phase 3 |
| Troriluzole | None of these genes | Phase 3 |
| Levetiracetam | None of these genes | Phase 2/3 |
| Tolcapone | None of these genes | Phase 2/3 |
| Acetylcysteine | None of these genes | Phase 2 |
| Agomelatine | None of these genes | Phase 2 |
| Aripiprazole | None of these genes | Phase 2 |
| Aticaprant | None of these genes | Phase 2 |
| Azithromycin | None of these genes | Phase 2 |
| Bitopertin | None of these genes | Phase 2 |
| Cannabidiol | None of these genes | Phase 2 |
| Celecoxib | None of these genes | Phase 2 |
| Dextromethorphan | None of these genes | Phase 2 |
| Dronabinol | None of these genes | Phase 2 |
| Flumazenil | None of these genes | Phase 2 |
| Ketamine | None of these genes | Phase 2 |
| Mavoglurant | None of these genes | Phase 2 |
| Methamphetamine | None of these genes | Phase 2 |
| Midazolam | None of these genes | Phase 2 |
| Midomafetamine | None of these genes | Phase 2 |
| Minocycline | None of these genes | Phase 2 |
| Naltrexone | None of these genes | Phase 2 |
| Nitrogen | None of these genes | Phase 2 |
| Nitrous Oxide | None of these genes | Phase 2 |
| Ondansetron | None of these genes | Phase 2 |
| Oxytocin | None of these genes | Phase 2 |
| Paliperidone | None of these genes | Phase 2 |
| Penicillin G | None of these genes | Phase 2 |
| Pramipexole | None of these genes | Phase 2 |
| Psilocybin | None of these genes | Phase 2 |
| Riluzole | None of these genes | Phase 2 |
| Risperidone | None of these genes | Phase 2 |
| Rituximab | None of these genes | Phase 2 |
| Sarcosine | None of these genes | Phase 2 |
| Secretin | None of these genes | Phase 2 |
| St. John'S Wort | None of these genes | Phase 2 |
| Valbenazine | None of these genes | Phase 2 |
| Venlafaxine | None of these genes | Phase 2 |
| Xenon | None of these genes | Phase 2 |
| Nabilone | None of these genes | Phase 1/2 |
| Lorazepam | None of these genes | Phase 1 |
| Acamprosate | None of these genes | Unknown |
| Caffeine | None of these genes | Unknown |
| Citalopram | None of these genes | Unknown |
| Dextroamphetamine | None of these genes | Unknown |
| Duloxetine | None of these genes | Unknown |
| Esketamine | None of these genes | Unknown |
| Glycine | None of these genes | Unknown |
| Olive Oil | None of these genes | Unknown |
| Omega-3 Fatty Acids | None of these genes | Unknown |
| Pyridoxine | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.