Comparative

Human disease

rheumatoid arthritis

MONDO:0008383

Mondo defines it as: “A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.”

1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.

Animal diseases

By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.

OMIA group Name Found by Species The chain reached Score
67 Arthritis, rheumatoid OMIA's OMIM numbers 1 Human disease 34.0

Human genes

Each human gene of these disease groups that Open Targets links to this disease.

Open Targets links none of these groups' human genes to this disease.

Drugs tested for this disease

Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.

Drug Acts on Latest stage for this disease
Abatacept None of these genes Approved
Aceclofenac None of these genes Approved
Adalimumab None of these genes Approved
Alclofenac None of these genes Approved
Anakinra None of these genes Approved
Auranofin None of these genes Approved
Azathioprine None of these genes Approved
Baricitinib None of these genes Approved
Canakinumab None of these genes Approved
Celecoxib None of these genes Approved
Certolizumab None of these genes Approved
Certolizumab Pegol None of these genes Approved
Cortisone Acetate None of these genes Approved
Cyclosporine None of these genes Approved
Dexamethasone None of these genes Approved
Dexamethasone Phosphoric Acid None of these genes Approved
Diclofenac None of these genes Approved
Diflunisal None of these genes Approved
Dimethyl Sulfoxide None of these genes Approved
Esomeprazole None of these genes Approved
Etanercept None of these genes Approved
Etodolac None of these genes Approved
Etofenamate None of these genes Approved
Etoricoxib None of these genes Approved
Famotidine None of these genes Approved
Fenoprofen None of these genes Approved
Filgotinib None of these genes Approved
Flurbiprofen None of these genes Approved
Gold Sodium Thiomalate None of these genes Approved
Golimumab None of these genes Approved
Hydrocortisone None of these genes Approved
Hydroxychloroquine None of these genes Approved
Ibuprofen None of these genes Approved
Iguratimod None of these genes Approved
Indomethacin None of these genes Approved
Infliximab None of these genes Approved
Inosine None of these genes Approved
Isopropyl Alcohol None of these genes Approved
Ketoprofen None of these genes Approved
Leflunomide None of these genes Approved
Meclofenamic Acid None of these genes Approved
Meloxicam None of these genes Approved
Methotrexate None of these genes Approved
Methylprednisolone None of these genes Approved
Methylprednisolone Acetate None of these genes Approved
Methylprednisolone Hemisuccinate None of these genes Approved
Misoprostol None of these genes Approved
Nabumetone None of these genes Approved
Naproxen None of these genes Approved
Niflumic Acid None of these genes Approved
Omeprazole None of these genes Approved
Oxaprozin None of these genes Approved
Ozoralizumab None of these genes Approved
Peficitinib None of these genes Approved
Penicillamine None of these genes Approved
Piroxicam None of these genes Approved
Prasterone None of these genes Approved
Prednisolone None of these genes Approved
Prednisone None of these genes Approved
Rituximab None of these genes Approved
Salsalate None of these genes Approved
Sarilumab None of these genes Approved
Sulfasalazine None of these genes Approved
Sulindac None of these genes Approved
Tenoxicam None of these genes Approved
Tocilizumab None of these genes Approved
Tofacitinib None of these genes Approved
Tolmetin None of these genes Approved
Triamcinolone Acetonide None of these genes Approved
Trientine None of these genes Approved
Upadacitinib None of these genes Approved
Valdecoxib None of these genes Approved
Amiprilose None of these genes Awaiting approval
Bucillamine None of these genes Phase 3
Chloroquine None of these genes Phase 3
Cilengitide None of these genes Phase 3
Cilostazol None of these genes Phase 3
Cipemastat None of these genes Phase 3
Corticotropin None of these genes Phase 3
Diosmin None of these genes Phase 3
Ergocalciferol None of these genes Phase 3
Escitalopram None of these genes Phase 3
Eszopiclone None of these genes Phase 3
Fish Oil None of these genes Phase 3
Folic Acid None of these genes Phase 3
Fostamatinib None of these genes Phase 3
Gamolenic Acid None of these genes Phase 3
Glucosamine None of these genes Phase 3
Gw-406381 None of these genes Phase 3
Hesperidin None of these genes Phase 3
Icosapent None of these genes Phase 3
Ivarmacitinib None of these genes Phase 3
Levilimab None of these genes Phase 3
Levocarnitine None of these genes Phase 3
Losartan None of these genes Phase 3
Lumiracoxib None of these genes Phase 3
Minocycline None of these genes Phase 3
Mizoribine None of these genes Phase 3
Montelukast None of these genes Phase 3
Nerelimomab None of these genes Phase 3
Nicorandil None of these genes Phase 3
Nitazoxanide None of these genes Phase 3
Ocrelizumab None of these genes Phase 3
Ofatumumab None of these genes Phase 3
Olokizumab None of these genes Phase 3
Omega-3 Fatty Acids None of these genes Phase 3
Otilimab None of these genes Phase 3
Paroxetine None of these genes Phase 3
Pelubiprofen None of these genes Phase 3
Piclidenoson None of these genes Phase 3
Resiniferatoxin None of these genes Phase 3
Resveratrol None of these genes Phase 3
Rupatadine None of these genes Phase 3
Satralizumab None of these genes Phase 3
Secukinumab None of these genes Phase 3
Sirukumab None of these genes Phase 3
Sivelestat None of these genes Phase 3
Spermidine None of these genes Phase 3
Spironolactone None of these genes Phase 3
Tabalumab None of these genes Phase 3
Tacrolimus Anhydrous None of these genes Phase 3
Telitacicept None of these genes Phase 3
Tenidap None of these genes Phase 3
Teriflunomide None of these genes Phase 3
Triamcinolone Hexacetonide None of these genes Phase 3
Ustekinumab None of these genes Phase 3
Vanadate None of these genes Phase 3
Varespladib Methyl None of these genes Phase 3
Zemprocitinib None of these genes Phase 3
Chromium None of these genes Phase 2/3
Decernotinib None of these genes Phase 2/3
Masitinib None of these genes Phase 2/3
Ramipril None of these genes Phase 2/3
Ubidecarenone None of these genes Phase 2/3
Vitamin E None of these genes Phase 2/3
Zanolimumab None of these genes Phase 2/3
2-(Aminomethyl)Phenol None of these genes Phase 2
Abbv-3373 None of these genes Phase 2
Acalabrutinib None of these genes Phase 2
Adalimumab Fosimdesonide None of these genes Phase 2
Adl-5859 None of these genes Phase 2
Afimkibart None of these genes Phase 2
Ak-106 None of these genes Phase 2
Aldesleukin None of these genes Phase 2
Alendronic Acid None of these genes Phase 2
Amelubant None of these genes Phase 2
Amg-108 None of these genes Phase 2
Aminocaproic Acid None of these genes Phase 2
Aminopterin None of these genes Phase 2
Andecaliximab None of these genes Phase 2
Anifrolumab None of these genes Phase 2
Apilimod None of these genes Phase 2
Apilimod None of these genes Phase 2
Apratastat None of these genes Phase 2
Apremilast None of these genes Phase 2
Apricoxib None of these genes Phase 2
Arginine None of these genes Phase 2
Atacicept None of these genes Phase 2
Atorvastatin None of these genes Phase 2
Azd5672 None of these genes Phase 2
Azd9056 None of these genes Phase 2
Baminercept None of these genes Phase 2
Bazlitoran None of these genes Phase 2
Belimumab None of these genes Phase 2
Belumosudil None of these genes Phase 2
Betamethasone None of these genes Phase 2
Betamethasone Phosphoric Acid None of these genes Phase 2
Biib-023 None of these genes Phase 2
Bimekizumab None of these genes Phase 2
Binimetinib None of these genes Phase 2
Blinatumomab None of these genes Phase 2
Bms-582949 None of these genes Phase 2
Bms-817399 None of these genes Phase 2
Bms-986142 None of these genes Phase 2
Bortezomib None of these genes Phase 2
Branebrutinib None of these genes Phase 2
Briobacept None of these genes Phase 2
Brodalumab None of these genes Phase 2
Burfiralimab None of these genes Phase 2
Calcium None of these genes Phase 2
Camobucol None of these genes Phase 2
Cannabidiol None of these genes Phase 2
Carnitine None of these genes Phase 2
Ccx354 None of these genes Phase 2
Ce-224535 None of these genes Phase 2
Cenplacel-L None of these genes Phase 2
Cetrorelix None of these genes Phase 2
Ch-1504 None of these genes Phase 2
Ch-1504 L-Isomer None of these genes Phase 2
Cholecalciferol None of these genes Phase 2
Clazakizumab None of these genes Phase 2
Clenoliximab None of these genes Phase 2
Colchicine None of these genes Phase 2
Cp-195543 None of these genes Phase 2
Cyclophosphamide Anhydrous None of these genes Phase 2
Dazodalibep None of these genes Phase 2
Dazukibart None of these genes Phase 2
Denosumab None of these genes Phase 2
Desloratadine None of these genes Phase 2
Diacerein None of these genes Phase 2
Digoxin None of these genes Phase 2
Dilmapimod None of these genes Phase 2
Dimethyl Fumarate None of these genes Phase 2
Dipyridamole None of these genes Phase 2
Disulfiram None of these genes Phase 2
Doramapimod None of these genes Phase 2
Dronabinol None of these genes Phase 2
Duvelisib None of these genes Phase 2
Edecesertib None of these genes Phase 2
Edicotinib None of these genes Phase 2
Efalizumab None of these genes Phase 2
Elasomeran None of these genes Phase 2
Eldelumab None of these genes Phase 2
Elsubrutinib None of these genes Phase 2
Emvododstat None of these genes Phase 2
Epoetin Alfa None of these genes Phase 2
Etaracizumab None of these genes Phase 2
Evobrutinib None of these genes Phase 2
Fenebrutinib None of these genes Phase 2
Fezakinumab None of these genes Phase 2
Fletikumab None of these genes Phase 2
Fludarabine None of these genes Phase 2
Fontolizumab None of these genes Phase 2
Fosbretabulin None of these genes Phase 2
Fosdagrocorat None of these genes Phase 2
Gevokizumab None of these genes Phase 2
Glpg-0259 None of these genes Phase 2
Glpg-3970 None of these genes Phase 2
Gsk2982772 None of these genes Phase 2
Gsk-3117391 None of these genes Phase 2
Guselkumab None of these genes Phase 2
Gw-274150 None of these genes Phase 2
Ianalumab None of these genes Phase 2
Ib-Meca None of these genes Phase 2
Imatinib None of these genes Phase 2
Incb-047986 None of these genes Phase 2
Inebilizumab None of these genes Phase 2
Iscalimab None of these genes Phase 2
Itacitinib None of these genes Phase 2
Itx-5061 Free Base None of these genes Phase 2
Ixekizumab None of these genes Phase 2
Jnj-39758979 None of these genes Phase 2
Keyhole Limpet Hemocyanin None of these genes Phase 2
Lanraplenib None of these genes Phase 2
Lenabasum None of these genes Phase 2
Lenzilumab None of these genes Phase 2
Leramistat None of these genes Phase 2
Losmapimod None of these genes Phase 2
Lovastatin None of these genes Phase 2
Loxoprofen None of these genes Phase 2
Lutikizumab None of these genes Phase 2
Lx-2931 None of these genes Phase 2
Maraviroc None of these genes Phase 2
Mavrilimumab None of these genes Phase 2
Metformin None of these genes Phase 2
Methoxsalen None of these genes Phase 2
Mizacorat None of these genes Phase 2
Mk-0873 None of these genes Phase 2
Mk-8457 None of these genes Phase 2
Monalizumab None of these genes Phase 2
Nabiximols None of these genes Phase 2
Namilumab None of these genes Phase 2
Natalizumab None of these genes Phase 2
Neflamapimod None of these genes Phase 2
Niacin None of these genes Phase 2
Niacinamide None of these genes Phase 2
Nipocalimab None of these genes Phase 2
Nnc0114-0006 None of these genes Phase 2
Obefazimod None of these genes Phase 2
Ocadusertib None of these genes Phase 2
Opigolix None of these genes Phase 2
Ordesekimab None of these genes Phase 2
Paclitaxel None of these genes Phase 2
Palmidrol None of these genes Phase 2
Pamapimod None of these genes Phase 2
Paridiprubart None of these genes Phase 2
Pateclizumab None of these genes Phase 2
Pd-360324 None of these genes Phase 2
Pegsunercept None of these genes Phase 2
Pentoxifylline None of these genes Phase 2
Peresolimab None of these genes Phase 2
Pg-760564 None of these genes Phase 2
Ph-797804 None of these genes Phase 2
Piclamilast None of these genes Phase 2
Pimagedine None of these genes Phase 2
Pirfenidone None of these genes Phase 2
Placulumab None of these genes Phase 2
Poison Oak Extract None of these genes Phase 2
Poseltinib None of these genes Phase 2
Pralnacasan None of these genes Phase 2
Prinaberel None of these genes Phase 2
Prt-2607 None of these genes Phase 2
Puerarin None of these genes Phase 2
Quetmolimab None of these genes Phase 2
Ravagalimab None of these genes Phase 2
(Rel)-P505-15 None of these genes Phase 2
Remtolumab None of these genes Phase 2
Resomelagon None of these genes Phase 2
Revamilast None of these genes Phase 2
Rimacalib None of these genes Phase 2
Ritlecitinib None of these genes Phase 2
Roflumilast None of these genes Phase 2
Rosiglitazone None of these genes Phase 2
Rosnilimab None of these genes Phase 2
Ruxolitinib None of these genes Phase 2
San-300 None of these genes Phase 2
Siponimod None of these genes Phase 2
Sodium Butyrate None of these genes Phase 2
Spebrutinib None of these genes Phase 2
Ssr-150106 None of these genes Phase 2
Tak-715 None of these genes Phase 2
Talmapimod None of these genes Phase 2
Taurursodiol None of these genes Phase 2
Temsirolimus None of these genes Phase 2
Tesnatilimab None of these genes Phase 2
Tetanus Toxoid None of these genes Phase 2
Tetracycline None of these genes Phase 2
Toreforant None of these genes Phase 2
Tozinameran None of these genes Phase 2
Tranexamic Acid None of these genes Phase 2
Tranilast None of these genes Phase 2
Tregalizumab None of these genes Phase 2
Triamcinolone None of these genes Phase 2
Troculeucel None of these genes Phase 2
Tru-015 None of these genes Phase 2
Tulisokibart None of these genes Phase 2
Ucb-1184197 None of these genes Phase 2
Ursodiol None of these genes Phase 2
Veltuzumab None of these genes Phase 2
Venlafaxine None of these genes Phase 2
Vidofludimus None of these genes Phase 2
Vobarilizumab None of these genes Phase 2
Vorbipiprant None of these genes Phase 2
Vx-702 None of these genes Phase 2
Zimlovisertib None of these genes Phase 2
Zunsemetinib None of these genes Phase 2
Allopurinol None of these genes Phase 1/2
Ask-8007 None of these genes Phase 1/2
Belatacept None of these genes Phase 1/2
Bevifimod None of these genes Phase 1/2
Bezisterim None of these genes Phase 1/2
Cannabichromene None of these genes Phase 1/2
Efavaleukin Alfa None of these genes Phase 1/2
Fexofenadine None of these genes Phase 1/2
Morphine None of these genes Phase 1/2
Naltrexone None of these genes Phase 1/2
Niclosamide None of these genes Phase 1/2
Obexelimab None of these genes Phase 1/2
Rapcabtagene Autoleucel None of these genes Phase 1/2
Rebamipide None of these genes Phase 1/2
Tgn-1412 None of these genes Phase 1/2
Ab-101 None of these genes Phase 1
Abbv-257 None of these genes Phase 1
Alemtuzumab None of these genes Phase 1
Amp-110 None of these genes Phase 1
Antilymphocyte Immunoglobulin (Horse) None of these genes Phase 1
Arry-797 None of these genes Phase 1
Avdoralimab None of these genes Phase 1
Ave-9940 None of these genes Phase 1
Azd-6703 None of these genes Phase 1
Bms-986104 None of these genes Phase 1
Briakinumab None of these genes Phase 1
Cabiralizumab None of these genes Phase 1
Cizutamig None of these genes Phase 1
Curcuminoids None of these genes Phase 1
Evt401 None of these genes Phase 1
Filgrastim None of these genes Phase 1
Genistein None of these genes Phase 1
Gimsilumab None of these genes Phase 1
Imvotamab None of these genes Phase 1
Interleukin 6 None of these genes Phase 1
Lenograstim None of these genes Phase 1
Mdx-1342 None of these genes Phase 1
Mycophenolate Mofetil None of these genes Phase 1
Nivolumab None of these genes Phase 1
Otelixizumab None of these genes Phase 1
Pacibekitug None of these genes Phase 1
Pegfilgrastim None of these genes Phase 1
Pexidartinib None of these genes Phase 1
Plamotamab None of these genes Phase 1
Plonmarlimab None of these genes Phase 1
Plx-5622 None of these genes Phase 1
R-1487 None of these genes Phase 1
Resolvin E1 None of these genes Phase 1
Roquinimex None of these genes Phase 1
Rozibafusp Alfa None of these genes Phase 1
Sc-57666 None of these genes Phase 1
Simvastatin None of these genes Phase 1
Sodium Chloride None of these genes Phase 1
Surovatamig None of these genes Phase 1
Tadekinig Alfa None of these genes Phase 1
Tak-020 None of these genes Phase 1
Tasocitinib None of these genes Phase 1
Tibulizumab None of these genes Phase 1
Timolumab None of these genes Phase 1
Tirabrutinib None of these genes Phase 1
Vamorolone None of these genes Phase 1
Vehicle None of these genes Phase 1
Vgx-1027 None of these genes Phase 1
Ziltivekimab None of these genes Phase 1
Zolacabtagene Autoleucel None of these genes Phase 1
Carvedilol None of these genes Early phase 1
Curcumin None of these genes Early phase 1
Fosmanogepix None of these genes Investigational new drug
Rosmarinic Acid None of these genes Investigational new drug
Tenosal None of these genes Investigational new drug
Romazarit None of these genes Preclinical
1 None of these genes Unknown
2vl None of these genes Unknown
Bupivacaine None of these genes Unknown
Calcitriol None of these genes Unknown
Citalopram None of these genes Unknown
Daclatasvir None of these genes Unknown
Dextromethorphan None of these genes Unknown
Dextrose None of these genes Unknown
Diazepam None of these genes Unknown
Doxycycline Anhydrous None of these genes Unknown
Entecavir Anhydrous None of these genes Unknown
Gamcemetinib None of these genes Unknown
Hyaluronidase None of these genes Unknown
Influenza A Virus, Split Virion None of these genes Unknown
Influenza Virus Vaccine None of these genes Unknown
Insulin Human None of these genes Unknown
Ledipasvir None of these genes Unknown
Melatonin None of these genes Unknown
Ombitasvir None of these genes Unknown
Paeoniflorin None of these genes Unknown
Paritaprevir None of these genes Unknown
Pioglitazone None of these genes Unknown
Raloxifene None of these genes Unknown
Ro-319790 None of these genes Unknown
Simeprevir None of these genes Unknown
Sofosbuvir None of these genes Unknown
Tnf-Alpha None of these genes Unknown
Udifitimod None of these genes Unknown
Vancomycin None of these genes Unknown
Velpatasvir None of these genes Unknown

The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.