Human disease
autoimmune thrombocytopenic purpura
Mondo defines it as: “An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin.”
2 disease groups in OMIA reach this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 1001 | Thrombocytopenia | OMIA's OMIM numbers | 6 | Human disease |
40.0
|
| 1104 | Thrombocytopenic purpura, autoimmune | OMIA's OMIM numbers | 2 | Human disease |
37.0
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
Open Targets links none of these groups' human genes to this disease.
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Cortisone Acetate | None of these genes | Approved |
| Dexamethasone | None of these genes | Approved |
| Dexamethasone Phosphoric Acid | None of these genes | Approved |
| Eltrombopag | None of these genes | Approved |
| Esomeprazole | None of these genes | Approved |
| Fostamatinib | None of these genes | Approved |
| Gma-161 | None of these genes | Approved |
| Human Immunoglobulin G | None of these genes | Approved |
| Prednisone | None of these genes | Approved |
| Rilzabrutinib | None of these genes | Approved |
| Romiplostim | None of these genes | Approved |
| Valziflocept | None of these genes | Approved |
| Vonoprazan | None of these genes | Approved |
| Avatrombopag | None of these genes | Phase 3 |
| Belimumab | None of these genes | Phase 3 |
| Betamethasone | None of these genes | Phase 3 |
| Betamethasone Phosphoric Acid | None of these genes | Phase 3 |
| Bortezomib | None of these genes | Phase 3 |
| Caffeic Acid | None of these genes | Phase 3 |
| Dapsone | None of these genes | Phase 3 |
| Decitabine | None of these genes | Phase 3 |
| Efgartigimod Alfa | None of these genes | Phase 3 |
| Hetrombopag Olamine | None of these genes | Phase 3 |
| Hydrocortisone | None of these genes | Phase 3 |
| Ianalumab | None of these genes | Phase 3 |
| Methylprednisolone | None of these genes | Phase 3 |
| Mezagitamab | None of these genes | Phase 3 |
| Mycophenolate Mofetil | None of these genes | Phase 3 |
| Orelabrutinib | None of these genes | Phase 3 |
| Oseltamivir | None of these genes | Phase 3 |
| Prednisolone | None of these genes | Phase 3 |
| Rafutrombopag | None of these genes | Phase 3 |
| Recombinant Human Thrombopoietin | None of these genes | Phase 3 |
| Rituximab | None of these genes | Phase 3 |
| Rozanolixizumab | None of these genes | Phase 3 |
| Sovleplenib | None of these genes | Phase 3 |
| Tretinoin | None of these genes | Phase 3 |
| Triamcinolone | None of these genes | Phase 3 |
| Atorvastatin | None of these genes | Phase 2/3 |
| Batoclimab | None of these genes | Phase 2/3 |
| Blisibimod | None of these genes | Phase 2/3 |
| Cyclophosphamide Anhydrous | None of these genes | Phase 2/3 |
| Vincristine | None of these genes | Phase 2/3 |
| Acetylcysteine | None of these genes | Phase 2 |
| Alemtuzumab | None of these genes | Phase 2 |
| Baricitinib | None of these genes | Phase 2 |
| Berberine | None of these genes | Phase 2 |
| Briobacept | None of these genes | Phase 2 |
| Cyclosporine | None of these genes | Phase 2 |
| Daclizumab | None of these genes | Phase 2 |
| Danazol | None of these genes | Phase 2 |
| Daratumumab | None of these genes | Phase 2 |
| Diacerein | None of these genes | Phase 2 |
| Diammonium Glycyrrhizinate | None of these genes | Phase 2 |
| Doxorubicin | None of these genes | Phase 2 |
| Fludarabine Phosphate | None of these genes | Phase 2 |
| Iguratimod | None of these genes | Phase 2 |
| Ixazomib | None of these genes | Phase 2 |
| Lumrotatug | None of these genes | Phase 2 |
| Lusutrombopag | None of these genes | Phase 2 |
| Obinutuzumab | None of these genes | Phase 2 |
| Riliprubart | None of these genes | Phase 2 |
| Rozrolimupab | None of these genes | Phase 2 |
| Sitagliptin | None of these genes | Phase 2 |
| Tacrolimus Anhydrous | None of these genes | Phase 2 |
| Terbutaline | None of these genes | Phase 2 |
| Teriflunomide | None of these genes | Phase 2 |
| Thalidomide | None of these genes | Phase 2 |
| Totrombopag | None of these genes | Phase 2 |
| Tucidinostat | None of these genes | Phase 2 |
| Upadacitinib | None of these genes | Phase 2 |
| Zanubrutinib | None of these genes | Phase 2 |
| Zetomipzomib | None of these genes | Phase 2 |
| Zolacabtagene Autoleucel | None of these genes | Phase 2 |
| Bevifimod | None of these genes | Phase 1/2 |
| Budoprutug | None of these genes | Phase 1/2 |
| Letolizumab | None of these genes | Phase 1/2 |
| Nadide | None of these genes | Phase 1/2 |
| Pirtobrutinib | None of these genes | Phase 1/2 |
| Povetacicept | None of these genes | Phase 1/2 |
| Veltuzumab | None of these genes | Phase 1/2 |
| Acetaminophen | None of these genes | Phase 1 |
| Diphenhydramine | None of these genes | Phase 1 |
| Inaticabtagene Autoleucel | None of these genes | Phase 1 |
| Sutimlimab | None of these genes | Phase 1 |
| Cholecalciferol | None of these genes | Early phase 1 |
| Amoxicillin | None of these genes | Unknown |
| Clarithromycin | None of these genes | Unknown |
| Darbepoetin Alfa | None of these genes | Unknown |
| Dazodalibep | None of these genes | Unknown |
| Epoetin Alfa | None of these genes | Unknown |
| Epoetin Beta | None of these genes | Unknown |
| Filgrastim | None of these genes | Unknown |
| Hydroxychloroquine | None of these genes | Unknown |
| Lenograstim | None of these genes | Unknown |
| Levofloxacin Anhydrous | None of these genes | Unknown |
| Luspatercept | None of these genes | Unknown |
| Metronidazole | None of these genes | Unknown |
| Pegfilgrastim | None of these genes | Unknown |
| Ripertamab | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.