Human disease
respiratory distress syndrome in premature infants
Mondo defines it as: “Infant acute respiratory distress syndrome is a lung disorder that affects premature infants caused by developmental insufficiency of surfactant production and structural immaturity of the lungs. The symptoms usually appear shortly after birth and may include tachypnea, tachycardia, chest wall retractions (recession), expiratory grunting, nasal flaring and cyanosis during breathing efforts.”
1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 101 | Respiratory distress syndrome | OMIA's OMIM numbers | 2 | Human disease |
34.0
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
Open Targets links none of these groups' human genes to this disease.
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Beractant | None of these genes | Approved |
| Colfosceril Palmitate | None of these genes | Approved |
| Lucinactant | None of these genes | Approved |
| Picrotoxin | None of these genes | Approved |
| Poractant Alfa | None of these genes | Approved |
| Calfactant | None of these genes | Phase 3 |
| Indomethacin | None of these genes | Phase 3 |
| Ketamine | None of these genes | Phase 3 |
| Nitric Oxide | None of these genes | Phase 3 |
| Propofol | None of these genes | Phase 3 |
| Retinol | None of these genes | Phase 3 |
| Ibuprofen | None of these genes | Phase 2/3 |
| Tyloxapol | None of these genes | Phase 2/3 |
| Dexamethasone | None of these genes | Phase 2 |
| Budesonide | None of these genes | Phase 1/2 |
| Bovactant | None of these genes | Phase 1 |
| Betamethasone | None of these genes | Unknown |
| Carnitine | None of these genes | Unknown |
| Fentanyl | None of these genes | Unknown |
| Levocarnitine | None of these genes | Unknown |
| Sodium Chloride | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.