Human disease
Wilson disease
Mondo defines it as: “A very rare inherited multisystemic disease presenting non-specific neurological, hepatic, psychiatric or osseo-muscular manifestations due to excessive copper deposition in the body.”
1 disease group in OMIA reaches this disease, through OMIA's own Mondo link or its OMIM numbers. The page shows the chain. It does not say whether an animal is a model of this disease.
Animal diseases
By natural-model score for this disease, highest first. The score says how complete and how well supported each chain is, by stated rules. How the score works.
| OMIA group | Name | Found by | Species | The chain reached | Score |
|---|---|---|---|---|---|
| 1071 | Wilson disease | Both routes | 7 | Target evidence |
95.2
|
Human genes
Each human gene of these disease groups that Open Targets links to this disease.
| Human gene | Score | Evidence |
|---|---|---|
| ATP7B | 0.86 | 4,946 |
Drugs tested for this disease
Each ChEMBL drug that has been tested for this disease, and the human genes above it acts on, if any. Open Targets gives some drugs, such as most enzyme replacement therapies, no target gene.
| Drug | Acts on | Latest stage for this disease |
|---|---|---|
| Penicillamine | None of these genes | Approved |
| Trientine | None of these genes | Approved |
| Zinc Acetate Anhydrous | None of these genes | Approved |
| Zinc Sulfate | None of these genes | Approved |
| Tiomolibdate Choline | None of these genes | Phase 3 |
| Tiomolibdate Diammonium | None of these genes | Phase 3 |
| Nimatpagene Pariparvovec | None of these genes | Phase 2 |
| Rivunatpagene Miziparvovec | None of these genes | Phase 1/2 |
| Succimer | None of these genes | Early phase 1 |
| Zinc Gluconate | None of these genes | Early phase 1 |
| Botulinum Toxin Type A | None of these genes | Unknown |
| Copper | None of these genes | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.