Comparative

Human gene

MPO myeloperoxidase

ENSG00000005381 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
2028 Myeloperoxidase deficiency dog MPO one to one Drug 63.4
for myeloperoxidase deficiency

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
myeloperoxidase deficiency MONDO:0009694 0.77 50

Drugs

Each ChEMBL drug that acts on this gene.

Drug How Latest stage
Verdiperstat inhibitor Phase 3

The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.