Comparative

Human gene

ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

ENSG00000005961 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
1000 Thrombasthenia dog ITGA2B one to one Drug 89.5
for Glanzmann thrombasthenia 1
1000 Thrombasthenia domestic cat ITGA2B one to one Drug 89.5
for Glanzmann thrombasthenia 1
1000 Thrombasthenia horse ITGA2B one to one Drug 89.5
for Glanzmann thrombasthenia 1

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
Glanzmann thrombasthenia 1 MONDO:0031332 0.84 414

Drugs

Each ChEMBL drug that acts on this gene.

Drug How Latest stage
Abciximab inhibitor Approved
Eptifibatide inhibitor Approved
Tirofiban inhibitor Approved
Zalunfiban inhibitor Phase 3
Tadocizumab antagonist Phase 2

The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.