Comparative

Human gene

ZIC2 Zic family member 2

ENSG00000043355 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
2307 Frontonasal dysplasia, ZIC2-related domestic cattle ZIC2 one to one Target evidence 57.6
for holoprosencephaly 5

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
holoprosencephaly 5 MONDO:0012322 0.82 422

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.