Human gene
ALX4 ALX homeobox 4
2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 810 | Polydactyly | dog | ALX4 | one to one | Target evidence |
62.2
|
| 1009 | Hemimelia, tibial | domestic cattle | ALX4 | one to one | Target evidence |
33.9
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| polydactyly of a triphalangeal thumb | MONDO:0008270 | 0.08 | 8 |
| tibia, hypoplasia or aplasia of, with polydactyly | MONDO:0008572 | 0.07 | 8 |
| tibial hemimelia | MONDO:0010144 | 0.05 | 4 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.