Human gene
F7 coagulation factor VII (serum prothrombin conversion accelerator)
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 361 | Factor VII deficiency | dog | F7 | one to one | Drug |
84.2
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| congenital factor VII deficiency | MONDO:0009211 | 0.78 | 164 |
Drugs
Each ChEMBL drug that acts on this gene.
| Drug | How | Latest stage |
|---|---|---|
| Eptacog Alfa (Activated) | exogenous protein | Approved |
| Eptacog Beta (Activated) | exogenous protein | Approved |
| Prothrombin Complex Concentrate | exogenous protein | Approved |
| Pci-27483 | inhibitor | Phase 2 |
| Coagulation Factor Vii Human | exogenous protein | Unknown |
| Eptacog Alfa Pegol (Activated) | exogenous protein | Unknown |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.