Comparative

Human gene

LAMC2 laminin subunit gamma 2

ENSG00000058085 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
1678 Epidermolysis bullosa, junctionalis, LAMC2-related domestic cattle LAMC2 one to one Drug 62.5
for junctional epidermolysis bullosa Herlitz type
1678 Epidermolysis bullosa, junctionalis, LAMC2-related horse LAMC2 one to one Drug 62.5
for junctional epidermolysis bullosa Herlitz type
1678 Epidermolysis bullosa, junctionalis, LAMC2-related sheep LAMC2 one to one Drug 62.5
for junctional epidermolysis bullosa Herlitz type

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
junctional epidermolysis bullosa Herlitz type MONDO:0009182 0.71 158
junctional epidermolysis bullosa, non-Herlitz type MONDO:0009180 0.62 22

Drugs

Each ChEMBL drug that acts on this gene.

Drug How Latest stage
Ocriplasmin hydrolytic enzyme Approved

The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.