Human gene
PKP1 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 1864 | Ectodermal dysplasia/skin fragility syndrome, PKP1-related | dog | PKP1 | one to one | Target evidence |
60.9
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| epidermolysis bullosa simplex due to plakophilin deficiency | MONDO:0011472 | 0.77 | 168 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.