Human gene
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2939 | Epileptic encephalopathy, CAD-related | domestic cat | CAD | one to one | Target evidence |
57.1
|
| 2201 | Haplotype with homozygous deficiency NH7, CAD-related | domestic cattle | CAD | one to one | Target evidence |
52.1
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| developmental and epileptic encephalopathy, 50 | MONDO:0014647 | 0.66 | 11 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.