Human gene

ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif 2

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group	Name	Species	Animal gene	Ortholog	The chain reached	Best score
328	Dermatosparaxis Ehlers-Danlos syndrome (dEDS), ADAMTS2-related	dog	ADAMTS2	one to one	Target evidence	66.0 for Ehlers-Danlos syndrome, dermatosparaxis type
328	Dermatosparaxis Ehlers-Danlos syndrome (dEDS), ADAMTS2-related	domestic cattle	ADAMTS2	one to one	Target evidence	66.0 for Ehlers-Danlos syndrome, dermatosparaxis type
328	Dermatosparaxis Ehlers-Danlos syndrome (dEDS), ADAMTS2-related	sheep	ADAMTS2	one to one	Target evidence	66.0 for Ehlers-Danlos syndrome, dermatosparaxis type

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease	Mondo	Score	Evidence
Ehlers-Danlos syndrome, dermatosparaxis type	MONDO:0009161	0.74	1,719

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.