Human gene
L2HGDH L-2-hydroxyglutarate dehydrogenase
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 1371 | L-2-hydroxyglutaricacidemia | dog | L2HGDH | one to one | Target evidence |
65.8
|
| 1371 | L-2-hydroxyglutaricacidemia | domestic cat | L2HGDH | one to one | Target evidence |
65.8
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| L-2-hydroxyglutaric aciduria | MONDO:0009370 | 0.82 | 297 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.