Human gene
F9 coagulation factor IX
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 438 | Haemophilia B | dog | F9 | one to one | Drug |
96.0
|
| 438 | Haemophilia B | domestic cat | F9 | one to one | Drug |
96.0
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| hemophilia B | MONDO:0010604 | 0.89 | 2,020 |
Drugs
Each ChEMBL drug that acts on this gene.
| Drug | How | Latest stage |
|---|---|---|
| Albutrepenonacog Alfa | exogenous protein | Approved |
| Coagulation Factor Ix Human | exogenous protein | Approved |
| Coagulation Factor Ix Recombinant Human | exogenous protein | Approved |
| Eftrenonacog Alfa | exogenous protein | Approved |
| Emicizumab | other | Approved |
| Etranacogene Dezaparvovec | exogenous protein | Approved |
| Fidanacogene Elaparvovec | exogenous gene | Approved |
| Nonacog Beta Pegol | exogenous protein | Approved |
| Prothrombin Complex Concentrate | exogenous protein | Approved |
| Valoctocogene Roxaparvovec | exogenous protein | Approved |
| Pegnivacogin | inhibitor | Phase 3 |
| Trenonacog Alfa | exogenous protein | Phase 3 |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.