Human gene
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 1917 | Polyneuropathy, ARHGEF10-related | dog | ARHGEF10 | one to one | Target evidence |
47.1
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| autosomal dominant slowed nerve conduction velocity | MONDO:0011998 | 0.52 | 44 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.