Human gene
MAN2B1 mannosidase, alpha, class 2B, member 1
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 625 | Mannosidosis, alpha | dog | MAN2B1 | one to one | Target evidence |
95.0
|
| 625 | Mannosidosis, alpha | domestic cat | MAN2B1 | one to one | Target evidence |
95.0
|
| 625 | Mannosidosis, alpha | domestic cattle | MAN2B1 | one to one | Target evidence |
95.0
|
| 625 | Mannosidosis, alpha | domestic guinea pig | Man2b1 | one to one | Target evidence |
95.0
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| alpha-mannosidosis | MONDO:0009561 | 0.86 | 1,829 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.