Comparative

Human gene

LMBR1 limb development membrane protein 1

ENSG00000105983 on Ensembl

2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
810 Polydactyly domestic cat LMBR1 one to one Target evidence 62.2
for polydactyly of a triphalangeal thumb
1612 Oligozeugodactyly chicken LMBR1 one to one Target evidence 52.2
for acheiropody

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
polydactyly of a triphalangeal thumb MONDO:0008270 0.78 138
tibia, hypoplasia or aplasia of, with polydactyly MONDO:0008572 0.67 10
acheiropody MONDO:0008700 0.66 19

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.