Comparative

Human gene

SETX senataxin

ENSG00000107290 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
3058 Ataxia, SETX-related dog SETX one to one Target evidence 58.1
for spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2 MONDO:0018996 0.83 1,942
amyotrophic lateral sclerosis type 4 MONDO:0011223 0.79 1,844

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.