Comparative

Human gene

CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1

ENSG00000111012 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
837 Vitamin D-deficiency rickets, type IA dog CYP27B1 one to one Target evidence 68.7
for vitamin D-dependent rickets, type 1A
837 Vitamin D-deficiency rickets, type IA domestic cat CYP27B1 one to one Target evidence 68.7
for vitamin D-dependent rickets, type 1A
837 Vitamin D-deficiency rickets, type IA pig CYP27B1 one to one Target evidence 68.7
for vitamin D-dependent rickets, type 1A

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
vitamin D-dependent rickets, type 1A MONDO:0020723 0.82 177

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.