Human gene
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 1244 | Retinal degeneration II | dog | GNB3 | one to one | Drug |
77.9
|
| 1368 | Retinopathy globe enlarged | chicken | GNB3 | one to one | Target evidence |
51.5
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| congenital stationary night blindness 1H | MONDO:0014872 | 0.64 | 12 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.