Comparative

Human gene

GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3

ENSG00000111664 on Ensembl

2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
1244 Retinal degeneration II dog GNB3 one to one Drug 77.9
for Leber congenital amaurosis 10
1368 Retinopathy globe enlarged chicken GNB3 one to one Target evidence 51.5
for congenital stationary night blindness 1H

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
congenital stationary night blindness 1H MONDO:0014872 0.64 12

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.