Comparative

Human gene

ALDH5A1 aldehyde dehydrogenase 5 family, member A1

ENSG00000112294 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
2250 Succinic semialdehyde dehydrogenase deficiency, ALDH5A1-related dog ALDH5A1 one to one Drug 78.5
for succinic semialdehyde dehydrogenase deficiency

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
succinic semialdehyde dehydrogenase deficiency MONDO:0010083 0.84 847

Drugs

Each ChEMBL drug that acts on this gene.

Drug How Latest stage
Valproic Acid inhibitor Approved

The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.