Human gene
COL7A1 collagen type VII alpha 1
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 341 | Epidermolysis bullosa, dystrophic | domestic cattle | COL7A1 | one to one | Drug |
85.2
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| recessive dystrophic epidermolysis bullosa | MONDO:0009179 | 0.86 | 955 |
| generalized dominant dystrophic epidermolysis bullosa | MONDO:0007549 | 0.84 | 382 |
| transient bullous dermolysis of the newborn | MONDO:0007548 | 0.77 | 287 |
| epidermolysis bullosa simplex 5A, Ogna type | MONDO:0007555 | 0.09 | 12 |
Drugs
Each ChEMBL drug that acts on this gene.
| Drug | How | Latest stage |
|---|---|---|
| Beremagene Geperpavec | exogenous gene | Approved |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.