Comparative

Human gene

UMPS uridine monophosphate synthetase

ENSG00000114491 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
262 Deficiency of uridine monophosphate synthase domestic cattle UMPS one to one Drug 81.1
for orotic aciduria

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
orotic aciduria MONDO:0009797 0.77 274

Drugs

Each ChEMBL drug that acts on this gene.

Drug How Latest stage
Azaribine inhibitor Approved

The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.