Comparative

Human gene

POMC proopiomelanocortin

ENSG00000115138 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
1258 Obesity dog POMC one to one Target evidence 41.8
for obesity due to congenital leptin deficiency

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
obesity due to congenital leptin deficiency MONDO:0013991 0.05 4

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.