Human gene
MFN2 mitofusin 2
2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 1106 | Axonopathy | domestic cattle | MFN2 | one to one | Target evidence |
58.7
|
| 2153 | Neuroaxonal dystrophy, MFN2-related | dog | MFN2 | one to one | Target evidence |
58.7
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| Charcot-Marie-Tooth disease type 2A2 | MONDO:0012231 | 0.85 | 164 |
| Charcot-Marie-Tooth disease, axonal, autosomal recessive, type 2a2b; | MONDO:0014906 | 0.81 | 79 |
| neuropathy, hereditary motor and sensory, type 6A | MONDO:0011002 | 0.81 | 66 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.