Comparative

Human gene

FASLG Fas ligand (TNF superfamily, member 6)

ENSG00000117560 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
2064 Autoimmune lymphoproliferative syndrome, FASLG-related domestic cat FASLG one to one Drug 56.0
for autoimmune lymphoproliferative syndrome type 1

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
autoimmune lymphoproliferative syndrome type 1 MONDO:0011158 0.70 213

Drugs

Each ChEMBL drug that acts on this gene.

Drug How Latest stage
Asunercept binding agent Phase 3

The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.