Human gene
APAF1 apoptotic peptidase activating factor 1
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 1 | Haplotype with homozygous deficiency HH1, APAF1-related | domestic cattle | APAF1 | one to one | Animal disease only |
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
Open Targets links this gene to none of the human diseases the disease groups reached.
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.