Human gene
PLP1 proteolipid protein 1
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 770 | Tremor, X-linked, PLP1-related | dog | PLP1 | one to one | Target evidence |
69.9
|
| 770 | Tremor, X-linked, PLP1-related | Rhesus monkey | PLP1 | one to one | Target evidence |
69.9
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| Pelizaeus-Merzbacher spectrum disorder | MONDO:0010714 | 0.85 | 624 |
| hereditary spastic paraplegia 2 | MONDO:0010733 | 0.83 | 332 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.