Human gene
IDUA iduronidase, alpha-L-
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 664 | Mucopolysaccharidosis I | dog | IDUA | one to one | Target evidence |
84.7
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| Hurler syndrome | MONDO:0011758 | 0.85 | 478 |
| Scheie syndrome | MONDO:0011760 | 0.85 | 493 |
| Hurler-Scheie syndrome | MONDO:0011759 | 0.85 | 238 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.