Human gene
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
2 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 2646 | Retinal atrophy, progressive, GUCY2D-related | dog | GUCY2D | one to one | Target evidence |
57.4
|
| 1929 | Retinal atrophy - Cone-rod dystrophy 6 | pig | GUCY2D | one to one | Target evidence |
31.8
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| Leber congenital amaurosis 1 | MONDO:0008764 | 0.81 | 1,570 |
| cone-rod dystrophy 6 | MONDO:0011143 | 0.76 | 1,450 |
Drugs
Each ChEMBL drug that acts on this gene.
No ChEMBL drug acts on this gene, among the genes with target evidence.