Human gene

PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta

4 disease groups in OMIA reach this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group	Name	Species	Animal gene	Ortholog	The chain reached	Best score
882	Retinal atrophy - Rod-cone dysplasia 1	dog	PDE6B	one to one	Human gene	29.0 for congenital stationary night blindness autosomal dominant 2
1669	Retinal atrophy - Rod-cone dysplasia 1a	dog	PDE6B	one to one	Human gene	29.0 for congenital stationary night blindness autosomal dominant 2
1674	Retinal atrophy - Cone-rod dystrophy 1	dog	PDE6B	one to one	Human gene	29.0 for congenital stationary night blindness autosomal dominant 2
2282	Retinal atrophy, progressive, PDE6B-related	dog	PDE6B	one to one	Human gene	29.0 for congenital stationary night blindness autosomal dominant 2

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Open Targets links this gene to none of the human diseases the disease groups reached.

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.