Comparative

Human gene

APC adenomatous polyposis coli

ENSG00000134982 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
1916 Familial adenomatous polyposis dog APC one to one Target evidence 66.4
for familial adenomatous polyposis 1
1916 Familial adenomatous polyposis horse APC one to one Target evidence 66.4
for familial adenomatous polyposis 1
1916 Familial adenomatous polyposis pig APC one to one Target evidence 66.4
for familial adenomatous polyposis 1

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
familial adenomatous polyposis 1 MONDO:0021056 0.84 12,427

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.