Comparative

Human gene

PNPLA8 patatin like phospholipase domain containing 8

ENSG00000135241 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
827 Myeloencephalopathy, progressive degenerative, PNPLA8-related dog PNPLA8 one to one Target evidence 57.6
for mitochondrial myopathy-lactic acidosis-deafness syndrome
827 Myeloencephalopathy, progressive degenerative, PNPLA8-related domestic cattle PNPLA8 one to one Target evidence 57.6
for mitochondrial myopathy-lactic acidosis-deafness syndrome

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
mitochondrial myopathy-lactic acidosis-deafness syndrome MONDO:0016825 0.73 39

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.