Comparative

Human gene

MYO7A myosin VIIA

ENSG00000137474 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
2148 Deafness, bilateral, and vestibular dysfunction, MYO7A-related dog MYO7A one to one Target evidence 61.2
for Usher syndrome type 1B
2148 Deafness, bilateral, and vestibular dysfunction, MYO7A-related pig MYO7A one to one Target evidence 61.2
for Usher syndrome type 1B

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
Usher syndrome type 1B MONDO:0700087 0.84 933
autosomal recessive nonsyndromic hearing loss 2 MONDO:0010807 0.79 954
autosomal dominant nonsyndromic hearing loss 11 MONDO:0011032 0.77 607

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.