Comparative

Human gene

FGD4 FYVE, RhoGEF and PH domain containing 4

ENSG00000139132 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
2374 Charcot Marie Tooth disease, FGD4-related domestic cattle FGD4 one to one Target evidence 55.2
for Charcot-Marie-Tooth disease type 4H

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
Charcot-Marie-Tooth disease type 4H MONDO:0012250 0.75 230

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.