Comparative

Human gene

PDX1 pancreatic and duodenal homeobox 1

ENSG00000139515 on Ensembl

1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.

Animal diseases

By each group's best natural-model score, highest first. How the score works.

OMIA group Name Species Animal gene Ortholog The chain reached Best score
2552 Pancreatic agenesis, PDX1-related pig PDX1 one to one Target evidence 51.1
for type 2 diabetes mellitus

Target evidence

Each Open Targets association between this gene and a human disease that a disease group reached.

Human disease Mondo Score Evidence
pancreatic agenesis 1 MONDO:0024547 0.73 75
maturity-onset diabetes of the young type 4 MONDO:0011667 0.71 131
type 2 diabetes mellitus MONDO:0005148 0.60 519

Drugs

Each ChEMBL drug that acts on this gene.

No ChEMBL drug acts on this gene, among the genes with target evidence.