Human gene
COL6A1 collagen, type VI, alpha 1
1 disease group in OMIA reaches this gene, through the animal gene that Ensembl gives as its ortholog. The page shows the chain. It does not say whether an animal is a model of a human disease.
Animal diseases
By each group's best natural-model score, highest first. How the score works.
| OMIA group | Name | Species | Animal gene | Ortholog | The chain reached | Best score |
|---|---|---|---|---|---|---|
| 1967 | Muscular dystrophy, Ullrich type, COL6A1-related | dog | COL6A1 | one to one | Drug |
59.1
|
Target evidence
Each Open Targets association between this gene and a human disease that a disease group reached.
| Human disease | Mondo | Score | Evidence |
|---|---|---|---|
| Ullrich congenital muscular dystrophy 1A | MONDO:0009681 | 0.79 | 99 |
Drugs
Each ChEMBL drug that acts on this gene.
| Drug | How | Latest stage |
|---|---|---|
| Collagenase Clostridium Histolyticum | hydrolytic enzyme | Approved |
| Ocriplasmin | hydrolytic enzyme | Approved |
The drug data is ChEMBL's, under CC BY-SA 3.0, and came through Open Targets release 26.09.